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肌浆网的结构。

Structure of sarcoplasmic reticulum.

作者信息

Franzini-Armstrong C

出版信息

Fed Proc. 1980 May 15;39(7):2403-9.

PMID:7371874
Abstract

A classification of the sarcoplasmic reticulum (SR) membrane into areas devoted to different functions is described. The junctional (j) SR is covered by feet, it faces towards the transverse tubules, and it is probably devoted to receiving a signal from them. The free (f) SR contains the calcium pump. Isolated SR forms two fractions: light and heavy SR. The heavy fraction is composed of the lateral sacs of the triad, containing calsequestrin, and its membrane comprises both f and j SR. The light fraction is entirely composed of fSR membrane. It is proposed that the feet join jSR membrane to particles contained within the transverse tubules and that they play a direct role in excitation-contraction coupling.

摘要

本文描述了将肌浆网（SR）膜分为具有不同功能区域的分类方法。连接（j）SR被足状物覆盖，它面向横小管，可能专门用于接收来自横小管的信号。游离（f）SR含有钙泵。分离的SR形成两个部分：轻SR和重SR。重部分由三联体的侧囊组成，含有肌集钙蛋白，其膜包含f SR和j SR。轻部分完全由f SR膜组成。有人提出，足状物将j SR膜与横小管内的颗粒连接起来，并且它们在兴奋-收缩偶联中起直接作用。

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