• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

甘露糖苷贮积症的尿寡糖

Urinary oligosaccharides of mannosidosis.

作者信息

Yamashita K, Tachibana Y, Mihara K, Okada S, Yabuuchi H, Kobata A

出版信息

J Biol Chem. 1980 Jun 10;255(11):5126-33.

PMID:7372628
Abstract

Nine oligosaccharide fractions were purified from the urine of mannosidosis patients by Bio-Gel P-4 column chromatography, paper chromatography, and paper electrophoresis. Studies using exoglycosidase digestion, methylation analysis, periodate oxidation, and acetolysis revealed that most of the fractions were mixtures of two or three isomeric oligosaccharides. The structures of a total of 16 oligosaccharides were elucidated to be as follows: (formula: see text).

摘要

通过Bio-Gel P-4柱色谱法、纸色谱法和纸电泳法从甘露糖苷贮积症患者的尿液中纯化出9种寡糖级分。使用外切糖苷酶消化、甲基化分析、高碘酸盐氧化和乙酰解的研究表明,大多数级分是两种或三种异构寡糖的混合物。总共16种寡糖的结构已阐明如下:(分子式:见正文)。

相似文献

1
Urinary oligosaccharides of mannosidosis.甘露糖苷贮积症的尿寡糖
J Biol Chem. 1980 Jun 10;255(11):5126-33.
2
Urinary oligosaccharides of GM1-gangliosidosis. Structures of oligosaccharides excreted in the urine of type 1 but not in the urine of type 2 patients.GM1神经节苷脂贮积症的尿寡糖。1型患者尿液中排泄的寡糖结构,而2型患者尿液中未排泄。
J Biol Chem. 1981 Aug 25;256(16):8485-90.
3
Structural analysis of the major caprine beta-mannosidosis urinary oligosaccharides.主要山羊β-甘露糖苷贮积症尿寡糖的结构分析
Biochim Biophys Acta. 1983 Aug 23;759(1-2):67-73. doi: 10.1016/0304-4165(83)90190-3.
4
Structural study of the carbohydrate moiety of bovine pancreatic ribonuclease B.
J Biochem. 1980 Jul;88(1):51-8.
5
Alpha-mannosidosis: analysis of urinary oligosaccharides with high performance liquid chromatography and diagnosis of a case with unusually mild presentation.α-甘露糖苷贮积症:用高效液相色谱法分析尿寡糖并诊断一例表现异常轻微的病例
Clin Genet. 1984 Mar;25(3):248-55. doi: 10.1111/j.1399-0004.1984.tb01985.x.
6
Structural characterization of novel complex oligosaccharides accumulated in the caprine beta-mannosidosis kidney. Occurrence of tetra- and pentasaccharides containing a beta-linked mannose residue at the nonreducing terminus.在山羊β-甘露糖苷贮积症肾脏中积累的新型复合寡糖的结构表征。在非还原末端含有β-连接甘露糖残基的四糖和五糖的出现。
J Biol Chem. 1985 Dec 5;260(28):15239-45.
7
Molecular characterization of Limulus polyphemus C-reactive protein. II. Asparagine-linked oligosaccharides.鲎C反应蛋白的分子特征。II. 天冬酰胺连接的寡糖。
Eur J Biochem. 1993 May 15;214(1):99-110. doi: 10.1111/j.1432-1033.1993.tb17901.x.
8
Structural studies of urinary oligosaccharides from patients with mannosidosis.甘露糖苷贮积症患者尿中寡糖的结构研究。
Arch Biochem Biophys. 1981 Apr 1;207(2):337-52. doi: 10.1016/0003-9861(81)90041-2.
9
Urinary oligosaccharides of GM1-gangliosidosis. Different excretion patterns of oligosaccharides in the urine of type 1 and type 2 subgroups.GM1神经节苷脂贮积症的尿寡糖。1型和2型亚组尿液中寡糖的不同排泄模式。
J Biol Chem. 1981 May 25;256(10):4789-98.
10
Oligosaccharides from placenta: early diagnosis of feline mannosidosis.胎盘寡糖:猫甘露糖苷贮积症的早期诊断
FEBS Lett. 1986 Jan 20;195(1-2):247-52. doi: 10.1016/0014-5793(86)80169-7.

引用本文的文献

1
Exo- and endoglycosidases revisited.重新审视外切糖苷酶和内切糖苷酶。
Proc Jpn Acad Ser B Phys Biol Sci. 2013;89(3):97-117. doi: 10.2183/pjab.89.97.
2
Analysis of urinary oligosaccharides in lysosomal storage disorders by capillary high-performance anion-exchange chromatography-mass spectrometry.采用毛细管高效阴离子交换色谱-质谱法分析溶酶体贮积症中的尿低聚糖。
Anal Bioanal Chem. 2012 Jun;403(6):1671-83. doi: 10.1007/s00216-012-5968-9. Epub 2012 Apr 20.
3
Alpha-mannosidosis.α-甘露糖苷贮积症
Orphanet J Rare Dis. 2008 Jul 23;3:21. doi: 10.1186/1750-1172-3-21.
4
Characterization of a human core-specific lysosomal {alpha}1,6-mannosidase involved in N-glycan catabolism.参与N-聚糖分解代谢的人核心特异性溶酶体α1,6-甘露糖苷酶的特性分析。
J Biol Chem. 2005 Nov 4;280(44):37204-16. doi: 10.1074/jbc.M508930200. Epub 2005 Aug 22.
5
The core-specific lysosomal alpha(1-6)-mannosidase activity depends on aspartamidohydrolase activity.核心特异性溶酶体α(1-6)-甘露糖苷酶活性取决于天冬酰胺酶活性。
Biochem J. 1994 Feb 1;297 ( Pt 3)(Pt 3):463-6. doi: 10.1042/bj2970463.
6
Structure of carbohydrate unit A or porcine thyroglobulin.碳水化合物单元A或猪甲状腺球蛋白的结构。
Biochem J. 1981 Jun 1;195(3):691-9. doi: 10.1042/bj1950691.
7
Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups.溶酶体酶中的磷酸化寡糖:α-N-乙酰葡糖胺(1)磷酸(6)甘露糖二酯基团的鉴定。
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7074-8. doi: 10.1073/pnas.77.12.7074.
8
The catabolism of mammalian glycoproteins. Comparison of the storage products in bovine, feline and human mannosidosis.哺乳动物糖蛋白的分解代谢。牛、猫和人类甘露糖苷贮积症中储存产物的比较。
Biochem J. 1983 Dec 1;215(3):573-9. doi: 10.1042/bj2150573.
9
The storage products in genetic and swainsonine-induced human mannosidosis.遗传性和苦马豆素诱导的人类甘露糖苷贮积症中的储存产物。
Biochem J. 1983 Dec 1;215(3):693-6. doi: 10.1042/bj2150693.
10
Structural analysis of the major urinary oligosaccharides in feline alpha-mannosidosis.猫α-甘露糖苷贮积症中主要尿低聚糖的结构分析
Biochem J. 1986 Feb 1;233(3):899-904. doi: 10.1042/bj2330899.