莱茵衣藻瘫痪突变体中的超大鞭毛膜蛋白。
Oversized flagellar membrane protein in paralyzed mutants of Chlamydomonas reinhardrii.
作者信息
Jarvik J W, Rosenbaum J L
出版信息
J Cell Biol. 1980 May;85(2):258-72. doi: 10.1083/jcb.85.2.258.
Abstract
A mutant strain of Chlamydomonas reinhardtii is shown to possess an oversized flagellar membrane protein. The mutant has paralyzed flagella, is temperature sensitive for flagellar assembly, and has an abnormal axonemal protein composition. All phenotypes appear to derive from a single Mendelian mutation, and genetic analysis suggests that the mutation, which call ts222, is in the gene pfl. Because pf1 mutants are known to have radial-spoke defects (Piperno et al., 1977, Proc. Natl. Acad. Sci. U. S. A. 74:1600-1604; and Witman et al., 1978, J. Cell Biol. 76:729-797), a relation as yet undefined appears to exist between radial-spoke and flagellar membrane biogenesis.
摘要
一种莱茵衣藻突变株被证明拥有一种超大的鞭毛膜蛋白。该突变体的鞭毛麻痹，对鞭毛组装具有温度敏感性，并且轴丝蛋白组成异常。所有表型似乎都源自单一的孟德尔突变，遗传分析表明，这个名为ts222的突变位于pfl基因中。由于已知pf1突变体存在辐条缺陷（Piperno等人，1977年，《美国国家科学院院刊》74:1600 - 1604；以及Witman等人，1978年，《细胞生物学杂志》76:729 - 797），辐条与鞭毛膜生物发生之间似乎存在一种尚未明确的关系。
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