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[采用原始的一氧化二氮测定管,通过改良的凯蒂-施密特法研究脑血流量]

[Study of cerebral blood flow by the modified method of Kety-Schmidt using the original tube for determination of nitrous oxide].

作者信息

Zderkiewicz E

出版信息

Neurol Neurochir Pol. 1980 Jan-Feb;14(1):61-5.

PMID:7374898
Abstract

For simplifying the method of Kety-Schmidt used in measurements of cerebral blood flow a probe designed specially for this purpose was used for measuring the blood levels of nitrous oxide. The principles of the original method of Kety-Schmidt and the later proposed correction in calculations are described. The device for nitrous oxide determination called N2O-meter consists of a part for measurements and indication, to which cadmium-gold probes are attached fixed to the chambers used for blood investigations. The principle of the probe is based on demonstration of potential differences developing during N2O reduction on the cadmium electrode. Reduction of the volume of blood samples and the use of low concentration of nitrous oxide in the breathing mixture makes this method of cerebral blood flow determination safe for the patient and quick reading of the values increases the usefulness of the method under clinical conditions.

摘要

为简化用于测量脑血流量的凯蒂 - 施密特方法,专门为此设计了一种探头用于测量一氧化二氮的血药浓度。文中描述了凯蒂 - 施密特原始方法的原理以及后来提出的计算校正方法。用于测定一氧化二氮的装置称为N2O计,它由测量和指示部分组成,镉 - 金探头固定在该部分上,探头连接到用于血液检测的腔室。探头的原理基于在镉电极上一氧化二氮还原过程中产生的电位差的显示。减少血样体积以及在呼吸混合气中使用低浓度的一氧化二氮,使得这种脑血流量测定方法对患者安全,并且快速读取数值增加了该方法在临床条件下的实用性。

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