普鲁卡因青霉素在体内对淋球菌的灭活作用。一项初步研究。
Inactivation of gonococci by procaine penicillin in vivo. A pilot study.
作者信息
Rajan V S, Pang R, Sng E H
出版信息
Br J Vener Dis. 1978 Dec;54(6):398-9. doi: 10.1136/sti.54.6.398.
Abstract
A pilot study was carried out of 25 male volunteers with gonococcal urethritis. After intramuscular administration of 3 megaunits procaine penicillin and 1 g oral probenecid the urethral culture results for Neisseria gonorrhoeae remained positive up to five hours and thereafter became negative. These results may be useful in providing guidelines for advice on the duration of sexual abstinence following treatment. It is suggested that similar studies should be carried out in women.
摘要
对25名患有淋菌性尿道炎的男性志愿者进行了一项试点研究。肌肉注射300万单位普鲁卡因青霉素和口服1克丙磺舒后，淋病奈瑟菌的尿道培养结果在长达5小时内仍为阳性，此后转为阴性。这些结果可能有助于为治疗后禁欲持续时间的建议提供指导方针。建议对女性进行类似研究。
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本文引用的文献
1
How suitable are available pharmaceuticals for the treatment of sexually transmitted diseases? 1: Conditions presenting as genital discharges.现有药物对性传播疾病的治疗适用性如何？1：表现为生殖器分泌物的病症。
Br J Vener Dis. 1977 Oct;53(5):314-23. doi: 10.1136/sti.53.5.314.
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