Ukkonen P
Vox Sang. 1980;38(1):1-5. doi: 10.1111/j.1423-0410.1980.tb02322.x.
The persistence of hepatitis B surface antigen (HBsAg), e antigen (HGeAg) and antibodies to e antigen (anti-HBe) was studied retrospectively in 197 Finnish voluntary blood donors, who had been found positive for HBsAg by routine screening in 1970 or 1971. Two samples were available from each donor: the first was taken in 1970 or 1971 and the second in 1978; the average interval between the specimens was 7.6 years. All except one (99.5%) of the donors remained HGsAg carriers during the whole study period. HBeAg was detected initially in 3 (2%) cases, all of whom lost HBeAg after the follow-up, and 2 converted to anti-HBe-positive. Anti-HBe was found in the first samples of 158 (80%) HGsAg carriers, 154 (97%) of whom were still positive for anti-HBe in the second samples. These results suggest that the HBsAg carrier stage is stable as for the presence of HBsAg and anti-HBe.
对197名芬兰自愿献血者的乙肝表面抗原（HBsAg）、e抗原（HBeAg）及e抗原抗体（抗-HBe）的持续情况进行了回顾性研究，这些献血者在1970年或1971年的常规筛查中被发现HBsAg呈阳性。每位献血者有两份样本：第一份于1970年或1971年采集，第二份于1978年采集；两份样本之间的平均间隔时间为7.6年。在整个研究期间，除1人（99.5%）外，所有献血者均为HBsAg携带者。最初在3例（2%）中检测到HBeAg，所有这些病例在随访后均失去HBeAg，且2例转为抗-HBe阳性。在158例（80%）HBsAg携带者的第一份样本中发现了抗-HBe，其中154例（97%）在第二份样本中抗-HBe仍为阳性。这些结果表明，就HBsAg和抗-HBe的存在而言，HBsAg携带阶段是稳定的。
