细胞相关移植抗原对致敏小鼠脾细胞的迁移抑制作用：抗原呈递方法的影响
Migration inhibition of sensitized mouse spleen cells by cell-associated transplantation antigens: effect of method of antigen presentation.
作者信息
Jacobs S K, Preisler H D
出版信息
Clin Exp Immunol. 1978 Sep;33(3):386-88.
Abstract
The migration of specifically sensitized mouse spleen cells following exposure to allogeneic cells (antigen) in vitro was studied. The migration inhibition recorded when sensitized cells were admixed with allogeneic cells in capillary tubes (mix method) was compared to the inhibition observed when allogeneic cells were suspended in the culture chamber media (non-mix method). Specificity as well as a higher degree of migration inhibition were obtained using the mix method, suggesting that this method is superior to the nom-mix method.
摘要
研究了体外暴露于同种异体细胞（抗原）后特异性致敏小鼠脾细胞的迁移情况。将致敏细胞与同种异体细胞在毛细管中混合时记录到的迁移抑制（混合法）与同种异体细胞悬浮于培养室培养基中时观察到的抑制（非混合法）进行了比较。使用混合法可获得特异性以及更高程度的迁移抑制，这表明该方法优于非混合法。
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[Use of spleen cell migration inhibition tests in vitro for studying sensitization to transplants].[体外脾细胞迁移抑制试验在研究移植致敏中的应用]
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