Schor C M, Levi D M
Invest Ophthalmol Vis Sci. 1980 Jun;19(6):668-83.
Horizontal and vertical small-field optokinetic nystagmus (OKN) were examined in persons with strabismic or anisometropic amblyopia. Reduced velocity for the slow phase of OKN driven by temporalward and upward target motion presented monocularly was observed in both the amblyopic and nonamblyopic eyes of some subjects. Several experiments were conducted in search of a sensory disturbance of perceived motion sensitivity which could account for the abnormal OKN. Comparisons between the frequency response for OKN and the contrast sensitivity function for perceived motion revealed that amblyopes with asymmetric OKN had equal sensitivity to nasal and temporal target motion. Contrast thresholds for driving the temporal slow phase of OKN were elevated by over 1 log unit above contrast thresholds for perceived temporal target motion, whereas contrast thresholds for stimulating nasal movement and driving the nasalward slow phase of OKN were equal. Contrast sensitivity to nasal and temporal target motion was symmetrical at the fovea and parafovea of the amblyopic eye. These studies did not reveal a sensory a /mso observed in both eyes of persons with congenital strabismus without amblyopia and in the nondeprived eye in monocular congenital cataract. These observations suggest a relationship between directional asymmetries of OKN and the incomplete development of binocular vision.
对患有斜视性或屈光参差性弱视的患者进行了水平和垂直小视野视动性眼震（OKN）检查。在一些受试者的弱视眼和非弱视眼中，单眼呈现由颞侧和向上目标运动驱动的OKN慢相速度降低。进行了多项实验以寻找可能导致异常OKN的感知运动敏感性感觉障碍。对OKN频率响应和感知运动对比敏感度函数的比较表明，OKN不对称的弱视患者对鼻侧和颞侧目标运动具有相同的敏感性。驱动OKN颞侧慢相的对比阈值比感知颞侧目标运动的对比阈值高出1个对数单位以上，而刺激鼻侧运动和驱动OKN鼻侧慢相的对比阈值相等。弱视眼中央凹和旁中央凹对鼻侧和颞侧目标运动的对比敏感度是对称的。这些研究未发现感觉障碍。在无弱视的先天性斜视患者的双眼以及单眼先天性白内障患者的非剥夺眼中也观察到了同样的情况。这些观察结果表明OKN的方向不对称与双眼视觉发育不完全之间存在关联。
