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一名肾衰竭患者的血液透析相关性哮喘

Hemodialysis-associated asthma in a renal failure patient.

作者信息

Ei K, Hanai I, Horiuchi T, Hanai J, Gotoh H, Hirasawa Y, Gejyo F, Aizawa Y

出版信息

Nephron. 1980;25(5):247-8. doi: 10.1159/000181848.

Abstract

In a renal failure patient, asthma developed after 1 year hemodialytic treatment. The attack was exclusively associated with each hemodialysis. Skin test to the usual allergen such as house dusts or pollens was negative. The provocation test by inhaling acetate solution or oral intake of acetic acid was positive resulting in an increase in the pulmonary resistance, or asthmatic attack. This asthma disappeared completely after substitution of acetate in the hemodialysis by the use of a bicarbonate dialysate. Acetate might therefore precipitate the attack of asthma.

摘要

一名肾衰竭患者在接受1年血液透析治疗后出现哮喘。发作仅与每次血液透析相关。对常见过敏原如屋尘或花粉的皮肤试验为阴性。吸入醋酸溶液或口服醋酸进行激发试验呈阳性,导致肺阻力增加或哮喘发作。在血液透析中用碳酸氢盐透析液替代醋酸后,这种哮喘完全消失。因此,醋酸可能诱发哮喘发作。

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