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益康唑与克霉唑治疗外阴阴道念珠菌病的比较。

Comparison of econazole and clotrimazole in the treatment of vulvovaginal candidiasis.

作者信息

Brown D, Binder G L, Gardner H L, Wells J

出版信息

Obstet Gynecol. 1980 Jul;56(1):121-3.

PMID:7383476
Abstract

The therapeutic effectiveness of econazole and clotrimazole was evaluated in 178 women with clinical symptoms of vulvovaginal candidiasis and positive laboratory findings for Candida. The patients were randomly assigned to treatment with either 1% econazole vaginal cream or 100-mg clotrimazole vaginal tablets, each used once daily at bedtime for 7 days. The mycologic cure rates were comparable in the 2 treatment groups. There was a low incidence of local adverse reactions with both drugs.

摘要

对178名有外阴阴道念珠菌病临床症状且念珠菌实验室检查结果呈阳性的女性,评估了益康唑和克霉唑的治疗效果。患者被随机分配接受1%益康唑阴道乳膏或100毫克克霉唑阴道片治疗,均在睡前每日使用一次,持续7天。两个治疗组的真菌学治愈率相当。两种药物的局部不良反应发生率都很低。

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