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成年大鼠脑内脑组织移植

Transplantation of brain tissue in the brain of adult rats.

作者信息

Das G D, Hallas B H

出版信息

Experientia. 1978 Oct 15;34(10):1304-6. doi: 10.1007/BF01981434.

DOI:10.1007/BF01981434
PMID:738401
Abstract

Brain tissues obtained from rat embryos were transplanted in the forebrain and/or cerebellum of the adult rats. The transplants survived, grew and achieved normal cellular and cytoarchitectural differentiation. They had become anatomically integrated with the host brain. The animals did not show any obviously detectable abnormal behavior or pathology of the brain. The transplants survived as long as the animals did suggesting that they had become a part and parcel of the host brain.

摘要

从大鼠胚胎获取的脑组织被移植到成年大鼠的前脑和/或小脑中。移植组织存活、生长并实现了正常的细胞和细胞结构分化。它们在解剖学上已与宿主脑整合。这些动物未表现出任何明显可检测到的异常行为或脑部病理学特征。移植组织与动物存活时间一样长,这表明它们已成为宿主脑的一个组成部分。

相似文献

1
Transplantation of brain tissue in the brain of adult rats.成年大鼠脑内脑组织移植
Experientia. 1978 Oct 15;34(10):1304-6. doi: 10.1007/BF01981434.
2
Transplantation of brain tissue in the brain of rat. II. Growth characteristics of neocortical transplants in hosts of different ages.大鼠脑内脑组织移植。II. 不同年龄宿主中新皮质移植的生长特性。
Am J Anat. 1980 Jun;158(2):147-59. doi: 10.1002/aja.1001580205.
3
Behavioral effects of CNS transplants in the rat.中枢神经系统移植对大鼠行为的影响。
Brain Res. 1982 Jul 8;243(1):133-9. doi: 10.1016/0006-8993(82)91126-x.
4
Labeling of neural cells by gold-filled Sendai virus envelopes before intracerebral transplantation.在脑内移植前,用金填充的仙台病毒包膜标记神经细胞。
Science. 1988 Feb 5;239(4840):635-7. doi: 10.1126/science.2829355.
5
Transplantation of neural tissues in the brains of laboratory mammals: technical details and comments.实验哺乳动物脑内神经组织移植:技术细节与评论
Experientia. 1979 Feb 15;35(2):143-53. doi: 10.1007/BF01920580.
6
Transplantation of brain tissue in the brain of rat. I. Growth characteristics of neocortical transplants from embryos of different ages.大鼠脑内脑组织移植。I. 不同年龄胚胎新皮质移植的生长特性。
Am J Anat. 1980 Jun;158(2):135-45. doi: 10.1002/aja.1001580204.
7
Transplantation of embryonic neural tissue in the mammalian brain. I. Growth and differentiation of neuroblasts from various regions of the embryonic brain in the cerebellum of neonate rats.胚胎神经组织在哺乳动物脑内的移植。I. 新生大鼠小脑内来自胚胎脑不同区域的神经母细胞的生长与分化。
TIT J Life Sci. 1974;4(4):93-124.
8
The growth of embryonic brain tissue transplanted subcutaneously in rats.大鼠皮下移植胚胎脑组织的生长情况。
J Pathol. 1978 Oct;126(2):91-3. doi: 10.1002/path.1711260206.
9
Mitotic activity in adult rat brain induced by implantation of pieces of fetal rat brain and liver.植入胎鼠脑和肝组织诱导成年大鼠脑内的有丝分裂活性。
Neurosci Lett. 1979 Aug;13(3):265-70. doi: 10.1016/0304-3940(79)91505-2.
10
[Interneuronal connections in the transplantation of embryonic brain tissue into the brain of normal adult mammals and in pathology].[将胚胎脑组织移植到正常成年哺乳动物脑内及病理情况下的神经元间连接]
Dokl Akad Nauk SSSR. 1984 Sep-Oct;278(1):220-3.

引用本文的文献

1
Behavioural assessment of pinealectomy and foetal pineal gland transplantation in rats: Part II.大鼠松果体切除及胎儿松果体移植的行为学评估:第二部分。
Acta Neurochir (Wien). 1994;128(1-4):8-12. doi: 10.1007/BF01400646.
2
Morphological assessment in pinealectomy and foetal pineal gland transplantation in rats: Part I.大鼠松果体切除及胎儿松果体移植的形态学评估:第一部分。
Acta Neurochir (Wien). 1994;128(1-4):1-7. doi: 10.1007/BF01400645.
3
Freezing and transplantation of brain tissue in rats.大鼠脑组织的冷冻与移植

本文引用的文献

1
Transplanted precursors of nerve cells: their fate in the cerebellums of young rats.
Science. 1971 Aug 13;173(3997):637-8. doi: 10.1126/science.173.3997.637.
2
Transplantation of cerebellar tissue in the cerebellum of neonate rabbits.新生兔小脑内小脑组织移植
Brain Res. 1973 Feb 14;50(1):170-3. doi: 10.1016/0006-8993(73)90603-3.
3
Transplantation of embryonic neural tissue in the mammalian brain. I. Growth and differentiation of neuroblasts from various regions of the embryonic brain in the cerebellum of neonate rats.胚胎神经组织在哺乳动物脑内的移植。I. 新生大鼠小脑内来自胚胎脑不同区域的神经母细胞的生长与分化。
Experientia. 1980 Sep 15;36(9):1114-5. doi: 10.1007/BF01966001.
4
Transplantation into the mammalian adult spinal cord.移植到成年哺乳动物脊髓中。
Experientia. 1982 Jun 15;38(6):699-701. doi: 10.1007/BF01964104.
5
Reinnervation of the denervated adult spinal cord of rats by intraspinal transplants of embryonic brain stem neurons.通过胚胎脑干神经元脊髓内移植对成年去神经大鼠脊髓进行再神经支配
Cell Tissue Res. 1983;230(1):15-35. doi: 10.1007/BF00216024.
6
Tyrosine hydroxylase is expressed by neocortical neurons after transplantation.移植后,酪氨酸羟化酶由新皮质神经元表达。
Proc Natl Acad Sci U S A. 1986 Oct;83(19):7495-8. doi: 10.1073/pnas.83.19.7495.
7
Homotopic transplantation of embryonal neocortex tissue into damaged brains of adult rats.将胚胎新皮质组织同位移植到成年大鼠受损大脑中。
Neurosci Behav Physiol. 1989 Jul-Aug;19(4):324-9. doi: 10.1007/BF01236022.
8
Isochronic transplantation of neonatal grafts in the visual cortex of cats: responsiveness, ocular dominance and specificity of cortical cells to visual stimulation.猫视觉皮层新生儿移植物的等时移植:皮层细胞对视觉刺激的反应性、眼优势和特异性
Exp Brain Res. 1991;87(1):181-92. doi: 10.1007/BF00228519.
TIT J Life Sci. 1974;4(4):93-124.
4
[Regeneration of the cortex cerebri of Mus musculus. II. Morphological findings in regenerative processes after reimplantation of cortex segment].[小家鼠大脑皮质的再生。II. 皮质节段再植入后再生过程中的形态学发现]
Z Mikrosk Anat Forsch. 1969;81(1):32-70.
5
Transplantation of central and peripheral monoamine neurons to the adult rat brain: techniques and conditions for survival.
Brain Res. 1976 Sep 10;114(1):1-20. doi: 10.1016/0006-8993(76)91003-9.