Markert C, Rogers L W, Chiu J F
Digestion. 1978;18(3-4):261-5. doi: 10.1159/000198209.
Multiple colorectal adenocarcinomas were found in Sprague-Dawley rats after intrarectal injection of 1,2-dimethylhydrazine (DMH). These lesions along with mild hyperplasia of the surrounding mucosa developed within 34 weeks after either 3 or 8 injections of 250 mg DMH/kg body weight.
在向Sprague-Dawley大鼠直肠内注射1,2-二甲基肼（DMH）后，发现了多发性结肠腺癌。在以250毫克DMH/千克体重进行3次或8次注射后的34周内，这些病变连同周围黏膜的轻度增生一同出现。
