Mensah-Dwumah M, Djurhuus J C, Constantinou C E
Urol Int. 1980;35(3):161-6. doi: 10.1159/000280316.
There are regional variations of the amplitude, frequency and waveform of spontaneous contractions within the isolated renal pelvis and calyx of the multicalyceal pyeloureter of the pig. The contractility of these structures was studied in normal and hydronephrotic preparations. Tissues were obtained from normal and chronically obstructed animals. In 20 normal preparations, the contractile frequency of the renal pelvis was 4.9 +/- 2.1 contractions/min, while that of the calyx was 9.5 +/- 2.2 (mean +/- SD). The recorded amplitude was 0.95 +/- 0.92 and 0.45 +/- 0.61 g, respectively. The waveform of the calyceal contractility approximated the sinusoid demonstrating a slow rise and fall in tension, while the waveform of renal pelvic smooth muscle demonstrated a faster increase in tension. Obstruction and hydronephrosis produced a minimal alteration in the frequency and amplitude of the calyceal structures, 9.1 +/- 2.2 contractions/min and 0.71 +/- 0.49 g, respectively. Hydronephrotic renal pelves demonstrated a significant increase in the frequency of spontaneous contractility 8.0 +/- 4.2 contractions/min with no change in the mean amplitude of contraction 0.88 +/- 0.90 g. These data suggest that obstruction alters the frequency of isolated renal pelvic contraction so that they approximate the frequency of isolated calyceal contractions.
猪多肾盂输尿管分离的肾盂和肾盏内，自发性收缩的幅度、频率和波形存在区域差异。在正常和肾积水的标本中研究了这些结构的收缩性。组织取自正常和慢性梗阻的动物。在20个正常标本中，肾盂的收缩频率为4.9±2.1次/分钟，而肾盏的收缩频率为9.5±2.2次/分钟（平均值±标准差）。记录的幅度分别为0.95±0.92克和0.45±0.61克。肾盏收缩性的波形近似正弦波，显示张力缓慢上升和下降，而肾盂平滑肌的波形显示张力上升较快。梗阻和肾积水对肾盏结构的频率和幅度产生的改变极小，分别为9.1±2.2次/分钟和0.71±0.49克。肾积水的肾盂自发性收缩频率显著增加，为8.0±4.2次/分钟，而平均收缩幅度无变化，为0.88±0.90克。这些数据表明，梗阻改变了分离的肾盂收缩频率，使其接近分离的肾盏收缩频率。
