无机微量元素在牙釉质和牙本质形成中的功能作用：综述
Functional Role of Inorganic Trace Elements on Enamel and Dentin Formation: A Review.
作者信息
Shaik Izaz, Dasari Bhargavi, Shaik Asma, Doos Mina, Kolli Hemanadh, Rana Devyani, Tiwari Rahul V C
机构信息
MDS, DMD Student, Rutgers School of Dental Medicine, Newark, New Jersey, USA.
BDS, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India.
出版信息
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S952-S956. doi: 10.4103/jpbs.jpbs_392_21. Epub 2021 Nov 10.
Abstract
Calcium and phosphate are the major components of hydroxyapatite crystals that form the inorganic portion of the teeth. Apart from these, certain elements are present in little amounts in enamel and dentin of the human teeth. Although they are required in minute quantities, their absence may alter healthy development of enamel and dentin and may result in developmental tooth defects as well as dental caries. Furthermore, excessive intake of some trace elements may inversely affect tooth development and health. The exact of effects that trace elements have on teeth and oral health is still an unexplored territory. The present paper reviews the presence of trace elements in teeth and their role in tooth health and development.
摘要
钙和磷是构成牙齿无机部分的羟基磷灰石晶体的主要成分。除此之外，某些元素在人类牙齿的釉质和牙本质中含量极少。尽管它们需求量微小，但缺乏这些元素可能会改变釉质和牙本质的健康发育，并可能导致牙齿发育缺陷以及龋齿。此外，过量摄入某些微量元素可能会对牙齿发育和健康产生负面影响。微量元素对牙齿和口腔健康的确切影响仍是一个未被探索的领域。本文综述了牙齿中微量元素的存在情况及其在牙齿健康和发育中的作用。
相似文献
1
Functional Role of Inorganic Trace Elements on Enamel and Dentin Formation: A Review.无机微量元素在牙釉质和牙本质形成中的功能作用：综述
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S952-S956. doi: 10.4103/jpbs.jpbs_392_21. Epub 2021 Nov 10.
2
X-RAY SPECTRAL ANALYSIS OF DENTAL HARD TISSUE TRACE ELEMENTS (ELECTRON-MICROSCOPIC EXAMINATION).牙齿硬组织痕量元素的 X 射线能谱分析（电子显微镜检查）。
Georgian Med News. 2022 Mar(324):204-210.
3
Altered inorganic composition of dental enamel and dentin in primary teeth from girls with Turner syndrome.特纳综合征女童乳牙牙釉质和牙本质中无机成分的改变。
Eur J Oral Sci. 2010 Apr;118(2):183-90. doi: 10.1111/j.1600-0722.2010.00718.x.
4
Functional role of inorganic trace elements in dentin apatite tissue-part III: Se, F, Ag, and B.无机微量元素在牙本质磷灰石组织中的功能作用-第三部分：硒、氟、银和硼。
J Trace Elem Med Biol. 2022 Jul;72:126990. doi: 10.1016/j.jtemb.2022.126990. Epub 2022 May 12.
5
Exploring the Use of SEM-EDS Analysis to Measure the Distribution of Major, Minor, and Trace Elements in Bottlenose Dolphin (Tursiops truncatus) Teeth.探索使用扫描电子显微镜-能谱分析（SEM-EDS）来测量宽吻海豚（瓶鼻海豚，Tursiops truncatus）牙齿中主量、微量和痕量元素的分布。
Biol Trace Elem Res. 2022 May;200(5):2147-2159. doi: 10.1007/s12011-021-02809-9. Epub 2021 Jul 17.
6
Chapter 4: Development Defects of Enamel and Dentine and Coronal Caries.第四章：牙釉质和牙本质发育缺陷及冠部龋。
Monogr Oral Sci. 2023;31:37-49. doi: 10.1159/000530556. Epub 2023 Jun 26.
7
FAM20A is essential for amelogenesis, but is dispensable for dentinogenesis.FAM20A 对于成釉细胞的形成是必需的，但对于牙本质的形成是可有可无的。
J Mol Histol. 2019 Dec;50(6):581-591. doi: 10.1007/s10735-019-09851-x. Epub 2019 Oct 30.
8
Dentin matrix protein 1 and phosphate homeostasis are critical for postnatal pulp, dentin and enamel formation.牙本质基质蛋白 1 和磷酸盐稳态对出生后牙髓、牙本质和牙釉质的形成至关重要。
Int J Oral Sci. 2012 Dec;4(4):189-95. doi: 10.1038/ijos.2012.69. Epub 2012 Dec 21.
9
[Study of trace elements in bovine permanent teeth germ].[牛恒牙胚中微量元素的研究]
Kanagawa Shigaku. 1989 Jun;24(1):24-37.
10
Estimation of trace elements in sound and carious enamel of primary and permanent teeth by atomic absorption spectrophotometry: an in vitro study.用原子吸收分光光度法测定乳牙和恒牙健全及龋坏牙釉质中的微量元素：一项体外研究。
Indian J Dent Res. 2007 Oct-Dec;18(4):157-62. doi: 10.4103/0970-9290.35824.
引用本文的文献
1
[Research on the microhardness and microstructure of permanent tooth enamel in childhood].[关于儿童恒牙牙釉质显微硬度和微观结构的研究]
Hua Xi Kou Qiang Yi Xue Za Zhi. 2025 Aug 1;43(4):518-524. doi: 10.7518/hxkq.2025.2025161.
2
Evaluation of Effect of Interproximal Reduction in Enamel in Orthodontic Therapy: An Original Research.正畸治疗中牙釉质邻面减径效果的评估：一项原创研究
J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S448-S450. doi: 10.4103/jpbs.jpbs_1420_24. Epub 2025 Feb 25.
3
Selenium anion substitution in hydroxyapatite: chemo-mechanical effects compared with root canal dentin.羟基磷灰石中硒阴离子取代：与根管牙本质相比的化学机械效应
Odontology. 2025 May 11. doi: 10.1007/s10266-025-01111-7.
4
Advancements in nanohydroxyapatite: synthesis, biomedical applications and composite developments.纳米羟基磷灰石的进展：合成、生物医学应用及复合材料的发展
Regen Biomater. 2024 Nov 5;12:rbae129. doi: 10.1093/rb/rbae129. eCollection 2025.
5
Early childhood caries, climate change and the sustainable development goal 13: a scoping review.儿童期早期龋病、气候变化与可持续发展目标 13：范围综述。
BMC Oral Health. 2024 May 3;24(1):524. doi: 10.1186/s12903-024-04237-2.
6
The Stresses and Deformations in the Abfraction Lesions of the Lower Premolars Studied by the Finite Element Analyses: Case Report and Review of Literature.有限元分析研究下颌前磨牙磨损病变中的应力与变形：病例报告及文献综述
Diagnostics (Basel). 2024 Apr 9;14(8):788. doi: 10.3390/diagnostics14080788.
7
Comparison of Antibacterial Activity of Various Additives to Glass Ionomer Restoration: An Study.玻璃离子修复体中各种添加剂的抗菌活性比较：一项研究。
J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S189-S191. doi: 10.4103/jpbs.jpbs_450_23. Epub 2024 Feb 29.
8
Antibacterial Effect of Two Novel Sealants: A Laboratory-Based Study.两种新型封闭剂的抗菌作用：一项基于实验室的研究
J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S206-S208. doi: 10.4103/jpbs.jpbs_459_23. Epub 2024 Feb 29.
9
Microspatial distribution of trace elements in feline dental hard tissues: early life exposure to essential and toxic elements.猫科动物牙齿硬组织中微量元素的微观空间分布：生命早期对必需元素和有毒元素的暴露
Front Vet Sci. 2023 Jun 27;10:1204210. doi: 10.3389/fvets.2023.1204210. eCollection 2023.
10
Equine odontoclastic tooth resorption and hypercementosis (EOTRH): microspatial distribution of trace elements in hypercementosis-affected and unaffected hard dental tissues.马属动物牙吸收和过度钙化（EOTRH）：过度钙化影响和未影响硬组织牙齿中微量元素的微空间分布。
Sci Rep. 2023 Mar 28;13(1):5048. doi: 10.1038/s41598-023-32016-6.
本文引用的文献
1
Aging and trace elements in human coronal tooth dentine.人冠牙本质的老化与微量元素。
Sci Rep. 2020 Jun 19;10(1):9964. doi: 10.1038/s41598-020-66472-1.
2
Comparative assessment of the crystalline structures of powder and bulk human dental enamel by X-ray diffraction analysis.通过X射线衍射分析对粉末状和块状人类牙釉质晶体结构进行比较评估。
J Oral Biosci. 2019 Sep;61(3):173-178. doi: 10.1016/j.job.2019.06.003. Epub 2019 Jun 25.
3
Boron-rich diet may regulate blood lipid profile and prevent obesity: A non-drug and self-controlled clinical trial.富含硼的饮食可能调节血脂谱并预防肥胖：一项非药物和自我对照的临床试验。
J Trace Elem Med Biol. 2019 Jul;54:191-198. doi: 10.1016/j.jtemb.2019.04.021. Epub 2019 May 1.
4
Structural differences in enamel and dentin in human, bovine, porcine, and ovine teeth.人类、牛、猪和羊牙齿中牙釉质和牙本质的结构差异。
Ann Anat. 2018 Jul;218:7-17. doi: 10.1016/j.aanat.2017.12.012. Epub 2018 Mar 28.
5
The Tooth: Its Structure and Properties.牙齿：其结构与特性
Dent Clin North Am. 2017 Oct;61(4):651-668. doi: 10.1016/j.cden.2017.05.001.
6
Heavy metals in human teeth dentine: A bio-indicator of metals exposure and environmental pollution.人类牙齿牙本质中的重金属：金属暴露和环境污染的生物指标。
Chemosphere. 2017 Jun;176:221-230. doi: 10.1016/j.chemosphere.2017.02.114. Epub 2017 Feb 22.
7
Influence of trace elements on dental enamel properties: A review.
J Pak Med Assoc. 2017 Jan;67(1):116-120.
8
Prevention of dental caries through the use of fluoride--the WHO approach.通过使用氟化物预防龋齿——世界卫生组织的方法。
Community Dent Health. 2016 Jun;33(2):66-8.
9
Age-related differences in hair trace elements: a cross-sectional study in Orenburg, Russia.头发微量元素的年龄相关差异：俄罗斯奥伦堡的一项横断面研究。
Ann Hum Biol. 2016 Sep;43(5):438-44. doi: 10.3109/03014460.2015.1071424. Epub 2015 Sep 18.
10
In situ effect of titanium tetrafluoride and sodium fluoride on artificially decayed human enamel.四氟化钛和氟化钠对人工龋损人牙釉质的原位作用
Braz Dent J. 2014 Jan-Feb;25(1):28-32. doi: 10.1590/0103-6440201302329.
Zotero 插件