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Isochromosome 17q in two cases of acute blast transformation in myeloproliferative disorders.

作者信息

McDermott A, Romain D, Fraser I D, Scott G L

出版信息

Hum Genet. 1978 Dec 18;45(2):215-8. doi: 10.1007/BF00286966.

Abstract

Two cases of acute blast cell transformation in myeloproliferative disorders associated with a dicentric 17q isochromosome are reported. In both cases, the karyotypes also included a Philadelphia 9q;22q translocation, and in one case, an additional chromosome 8 (trisomy 8).

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