Coetzee A S
Arch Otolaryngol. 1980 Jul;106(7):405-9. doi: 10.1001/archotol.1980.00790310029007.
I describe 110 patients in whom diseased and destructed bone was restored to normal healthy bone. The first ten patients were healed by using bismuth-iodoform, and the following 100 patients were treated using the hemihydrate of calcium sulfate (CaSO4.2H3O). Both alloplasts were replaced in all patients by normal healthy cancellous bone within two to four months. It is a safe procedure in which bone regeneration is stimulated to a maximum rate. During June 1974, bismuth-iodoform was used as an allograft. On July 9, 1974, the first three operations in the history of otorhinolaryngology, to my knowledge, were performed using CaSO4. Normal physiologic absorption of CaSO4 occurs with the simultaneous deposition of autogenous cancellous bone. Calcium sulfate is an outstanding bone substitute, ensuring bone formation and giving results comparable with autogenous bone, if not better.
我描述了110例病变和受损骨骼恢复为正常健康骨骼的患者。前10例患者使用铋碘仿治愈，接下来的100例患者使用硫酸钙半水合物（CaSO₄·½H₂O）进行治疗。在两到四个月内，所有患者体内的这两种同种异体移植物均被正常健康的松质骨替代。这是一种安全的手术，能将骨再生刺激到最大速率。1974年6月，铋碘仿被用作同种异体移植物。据我所知，1974年7月9日，耳鼻喉科历史上首次进行了三例使用硫酸钙的手术。硫酸钙在自体松质骨同时沉积的情况下会发生正常的生理吸收。硫酸钙是一种出色的骨替代物，能确保骨形成，即便效果不比自体骨更好，也能与之相媲美。
