Brandes J M, Lightman A, Itskovitz J, Zinder O
Biol Neonate. 1980;38(1-2):66-70. doi: 10.1159/000241337.
Zinc concentration was determined in maternal serum and amniotic fluid during normal pregnancy. The nonpregnant zinc concentration in the serum of about 110 micrograms% decreases gradually during pregnancy to about half the normal level. Amniotic fluid zinc concentration shows a slight decrease and remains nearly constant until the 34th to 36th week of gestation, and then increases sharply (statistically significant) reaching the highest level at 40-42 weeks from the last menstrual period. The maternal-fetal metabolism of zinc, the various factors effecting zinc levels in maternal serum and amniotic fluid during pregnancy have been discussed in view of our results. These may serve as data base for further studies on the role of zinc in normal and pathological human pregnancies.
测定了正常妊娠期间母血清和羊水中的锌浓度。非妊娠时血清锌浓度约为110微克%，妊娠期间逐渐下降至正常水平的一半左右。羊水锌浓度略有下降，在妊娠34至36周前保持几乎恒定，然后急剧上升（具有统计学意义），在末次月经后的40 - 42周达到最高水平。根据我们的研究结果，讨论了锌的母胎代谢以及妊娠期间影响母血清和羊水锌水平的各种因素。这些结果可作为进一步研究锌在正常和病理性人类妊娠中作用的数据库。
