多发性硬化症中背柱的刺激
Stimulation of dorsal column in multiple sclerosis.
作者信息
Hawkes C H, Myke M, Desmond A, Bultitude M I, Kanegaonkar G S
出版信息
Br Med J. 1980 Mar 29;280(6218):889-91. doi: 10.1136/bmj.280.6218.889.
Abstract
The effect of stimulating the dorsal column in 19 selected patients with multiple sclerosis was studied in detail over two weeks. Before and during stimulation the patients were examined clinically; videotape recordings made of their movements; psychomotor performance tested; electrolaryngography performed; and urodynamic studies carried out. Improvement was seen in walking speed, power in certain muscle groups, chronic pain, and bladder function. The motor improvement was thought to be related to the effects of high motivation and practice, and therefore to be of doubtful importance. The changes in bladder function were more convincing and justify further study.
摘要
对19例多发性硬化症患者的背柱进行刺激的效果在两周内进行了详细研究。在刺激前和刺激过程中，对患者进行了临床检查；录制了他们运动的录像带；测试了心理运动表现；进行了电子喉描记术；并开展了尿动力学研究。在步行速度、某些肌肉群的力量、慢性疼痛和膀胱功能方面均有改善。运动功能的改善被认为与高度的积极性和练习的效果有关，因此其重要性存疑。膀胱功能的变化更具说服力，值得进一步研究。
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PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS.多发性硬化症治疗的实验性试验问题：多发性硬化症治疗实验性试验评估小组报告
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