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多发性硬化症中的背柱刺激:对膀胱的影响及长期研究结果

Dorsal column stimulation in multiple sclerosis: effects on bladder and long term findings.

作者信息

Hawkes C H, Beard R, Fawcett D, Paul E A, Thomas D G

出版信息

Br Med J (Clin Res Ed). 1983 Sep 17;287(6395):793-5. doi: 10.1136/bmj.287.6395.793.

Abstract

The effect of dorsal column stimulation on bladder function in 15 patients with established multiple sclerosis was analysed by urodynamic tests. Significant improvement in flow rate and urethral sphincter pressure was recorded in about two thirds. Of 31 patients examined over five years only 13 showed initial benefit from stimulation and were given permanent stimulators; of these, only three appeared to receive lasting benefit. Early complications occurred in nine patients and five had a relapse of their disease. These results suggest that at present stimulation of the dorsal column does not have a place in the routine management of multiple sclerosis.

摘要

通过尿动力学测试分析了15例确诊为多发性硬化症患者的背柱刺激对膀胱功能的影响。约三分之二的患者记录到流速和尿道括约肌压力有显著改善。在五年内接受检查的31例患者中,只有13例最初从刺激中获益并被植入永久性刺激器;其中只有3例似乎获得了持久益处。9例患者出现早期并发症,5例病情复发。这些结果表明,目前背柱刺激在多发性硬化症的常规治疗中并无用武之地。

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Stimulation of dorsal column in multiple sclerosis.多发性硬化症中背柱的刺激
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Chronic dorsal column stimulation: effects on H reflex and symptoms in a patient with multiple sclerosis.
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本文引用的文献

3
Stimulation of dorsal column in multiple sclerosis.多发性硬化症中背柱的刺激
Br Med J. 1980 Mar 29;280(6218):889-91. doi: 10.1136/bmj.280.6218.889.
5
Spinal cord stimulation in multiple sclerosis: clinical results.脊髓刺激治疗多发性硬化症:临床结果
J Neurol Neurosurg Psychiatry. 1980 Jan;43(1):1-14. doi: 10.1136/jnnp.43.1.1.
7
Spinal cord stimulation in the United Kingdom.英国的脊髓刺激疗法。
J Neurol Neurosurg Psychiatry. 1983 Apr;46(4):299-304. doi: 10.1136/jnnp.46.4.299.
8
The urethral pressure profile.尿道压力分布图。
Br J Urol. 1969 Apr;41(2):211-7. doi: 10.1111/j.1464-410x.1969.tb09925.x.
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Electrical stimulation in multiple sclerosis.多发性硬化症中的电刺激
Hosp Pract. 1976 Apr;11(4):51-8. doi: 10.1080/21548331.1976.11706516.

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