Hawkes C H, Beard R, Fawcett D, Paul E A, Thomas D G
Br Med J (Clin Res Ed). 1983 Sep 17;287(6395):793-5. doi: 10.1136/bmj.287.6395.793.
The effect of dorsal column stimulation on bladder function in 15 patients with established multiple sclerosis was analysed by urodynamic tests. Significant improvement in flow rate and urethral sphincter pressure was recorded in about two thirds. Of 31 patients examined over five years only 13 showed initial benefit from stimulation and were given permanent stimulators; of these, only three appeared to receive lasting benefit. Early complications occurred in nine patients and five had a relapse of their disease. These results suggest that at present stimulation of the dorsal column does not have a place in the routine management of multiple sclerosis.
通过尿动力学测试分析了15例确诊为多发性硬化症患者的背柱刺激对膀胱功能的影响。约三分之二的患者记录到流速和尿道括约肌压力有显著改善。在五年内接受检查的31例患者中，只有13例最初从刺激中获益并被植入永久性刺激器；其中只有3例似乎获得了持久益处。9例患者出现早期并发症，5例病情复发。这些结果表明，目前背柱刺激在多发性硬化症的常规治疗中并无用武之地。
