Gloor M, Gantner M, Wirth H, Schnyder U W
Dermatologica. 1980;160(3):175-9. doi: 10.1159/000250492.
60 male Syrian hamsters were treated on one ear with 2.5% selenium disulfide in a surfactant base and on the other ear with the same surfactant base. After treatment 15 animals were investigated by 3H-thymidine autoradiography, 15 animals by the colcemid method and 15 animals by the in vivo double labelling technique with 3H- and 14C-thymidine. In 15 animals the porportion of labeled cells was determined which still had contact with the basal lamina in the sebaceous gland 6 days after 3H-thymidine injection. Besides an increase in sebaceous gland size and in cell proliferation, a shortening of the S phase and a reduction of the labeled sebaceous gland cells which still have contact with the basal lamina of the sebaceous gland 6 days after 3H - thymidine injection were determined.
60只雄性叙利亚仓鼠，一只耳朵用含2.5%二硫化硒的表面活性剂基质处理，另一只耳朵用相同的表面活性剂基质处理。处理后，15只动物通过3H-胸腺嘧啶核苷放射自显影术进行研究，15只动物通过秋水仙酰胺法进行研究，15只动物通过3H-和14C-胸腺嘧啶核苷的体内双标记技术进行研究。在15只动物中，测定了在注射3H-胸腺嘧啶核苷6天后仍与皮脂腺基底层接触的标记细胞的比例。除了皮脂腺大小和细胞增殖增加外，还测定了S期缩短以及在注射3H-胸腺嘧啶核苷6天后仍与皮脂腺基底层接触的标记皮脂腺细胞减少。
