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大鼠和豚鼠暴露于硫酸雾、臭氧及其组合环境六个月后的影响。

The effects in rats and guinea pigs from six months exposures to sulfuric acid mist, ozone, and their combination.

作者信息

Cavender F L, Singh B, Cockrell B Y

出版信息

J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):485-92.

PMID:739227
Abstract

Rats and guinea pigs were exposed to 0.5 ppm ozone, 10 mg/m3 sulfuric acid mist, or their combination for 6 hrs/day, 5 days/week for six months. Exposure-related microscopic alterations were seen in the lungs of guinea pigs exposed to ozone alone or in combination with sulfuric acid mist. No other microscopic lesions were present in either rats or guinea pigs. No biologically meaningful synergistic effects were noted in animals exposed to the combination of ozone and sulfuric mist.

摘要

将大鼠和豚鼠每天暴露于0.5 ppm臭氧、10 mg/m³硫酸雾或它们的组合环境中,每天暴露6小时,每周暴露5天,持续6个月。在单独暴露于臭氧或同时暴露于硫酸雾的豚鼠肺部观察到与暴露相关的微观变化。大鼠和豚鼠均未出现其他微观病变。在暴露于臭氧和硫酸雾组合环境的动物中未观察到具有生物学意义的协同效应。

相似文献

1
The effects in rats and guinea pigs from six months exposures to sulfuric acid mist, ozone, and their combination.大鼠和豚鼠暴露于硫酸雾、臭氧及其组合环境六个月后的影响。
J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):485-92.
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J Toxicol Environ Health. 1977 Oct;3(3):521-33. doi: 10.1080/15287397709529584.
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Effects in rats and guinea pigs of six-month exposures to sulfuric acid mist, ozone, and their combination.大鼠和豚鼠暴露于硫酸雾、臭氧及其组合环境六个月的影响。
J Toxicol Environ Health. 1978 Sep-Nov;4(5-6):845-52. doi: 10.1080/15287397809529705.
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Sulfuric acid-layered ultrafine particles potentiate ozone-induced airway injury.硫酸层状超细颗粒会增强臭氧诱导的气道损伤。
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Effects of ozone and sulfuric acid aerosol on gas trapping in the guinea pig lung.臭氧和硫酸气溶胶对豚鼠肺中气体捕获的影响。
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Synergistic effects of air pollutants: ozone plus a respirable aerosol.空气污染物的协同效应:臭氧加可吸入气溶胶。
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Alteration of pulmonary macrophage intracellular pH following inhalation exposure to sulfuric acid/ozone mixtures.吸入硫酸/臭氧混合物后肺巨噬细胞细胞内pH值的变化。
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Influence of acid aerosol droplet size on structural changes in the rat lung caused by acute exposure to sulfuric acid and ozone.酸性气溶胶液滴大小对大鼠急性暴露于硫酸和臭氧所致肺部结构变化的影响。
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Deposition of sulfuric acid mist in the respiratory tracts of guinea pigs and rats.
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Environ Health Perspect. 1995 Mar;103 Suppl 2(Suppl 2):77-89. doi: 10.1289/ehp.95103s277.
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Respiratory tract changes in guinea pigs, rats, and mice following a single six-hour exposure to methyl isocyanate vapor.豚鼠、大鼠和小鼠单次暴露于异氰酸甲酯蒸气6小时后的呼吸道变化。
Environ Health Perspect. 1987 Jun;72:109-16. doi: 10.1289/ehp.8772109.