Cavender F L, Singh B, Cockrell B Y
J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):485-92.
Rats and guinea pigs were exposed to 0.5 ppm ozone, 10 mg/m3 sulfuric acid mist, or their combination for 6 hrs/day, 5 days/week for six months. Exposure-related microscopic alterations were seen in the lungs of guinea pigs exposed to ozone alone or in combination with sulfuric acid mist. No other microscopic lesions were present in either rats or guinea pigs. No biologically meaningful synergistic effects were noted in animals exposed to the combination of ozone and sulfuric mist.
将大鼠和豚鼠每天暴露于0.5 ppm臭氧、10 mg/m³硫酸雾或它们的组合环境中,每天暴露6小时,每周暴露5天,持续6个月。在单独暴露于臭氧或同时暴露于硫酸雾的豚鼠肺部观察到与暴露相关的微观变化。大鼠和豚鼠均未出现其他微观病变。在暴露于臭氧和硫酸雾组合环境的动物中未观察到具有生物学意义的协同效应。