Petersen R A, Robb R M
J Pediatr Ophthalmol Strabismus. 1978 Jul-Aug;15(4):246-50. doi: 10.3928/0191-3913-19780701-14.
In order to establish the rate of spontaneous resolution of congenital obstruction of the nasolacrimal duct, 50 infants, referred from a local pediatric group practice over a period of five years, were followed from the time of first symptoms until 8 to 13 months of age. Among the 50 infants, 65 nasolacrimal ducts were blocked and 58 ducts in 44 patients opened spontaneously. Only seven ducts in six patients required probing for relief of the obstruction. During the same period another seven patients from various referral sources were seen because of noninflammatory swelling of the lacrimal sac at birth. These patients were also found to have nasolacrimal duct obstruction, but early surgical intervention was required in six of the seven patients to relieve the distention of the sac.
为确定先天性鼻泪管阻塞的自然缓解率，对当地儿科联合诊所5年内转诊来的50例婴儿进行了随访，从首次出现症状开始，直至8至13个月龄。在这50例婴儿中，65条鼻泪管阻塞，44例患者的58条鼻泪管自然通畅。仅6例患者的7条鼻泪管需要探通以解除阻塞。同期，另有7例因出生时泪囊非炎性肿胀从不同转诊机构前来就诊的患者，也被发现存在鼻泪管阻塞，但这7例患者中有6例需要早期手术干预以缓解泪囊扩张。
