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人胎儿与成人红细胞谷胱甘肽S-转移酶活性的比较。

A comparison of erythrocyte glutathione S-transferase activity from human foetuses and adults.

作者信息

Strange R C, Johnston J D, Coghill D R, Hume R

出版信息

Biochem J. 1980 May 15;188(2):475-9. doi: 10.1042/bj1880475.

Abstract

Glutathione S-transferase activity was measured in partially purified haemolysates of erythrocytes from human foetuses and adults. Enzyme activity was present in erythrocytes obtained between 12 and 40 weeks of gestation. The catalytic properties of the enzyme from foetal cells were similar to those of the enzyme from adult erythrocytes, indicating that probably only one form of the erythrocytes enzyme exists throughout foetal and adult life.

摘要

在人胎儿和成人红细胞的部分纯化溶血产物中测量了谷胱甘肽S-转移酶活性。在妊娠12至40周期间获得的红细胞中存在酶活性。胎儿细胞中该酶的催化特性与成人红细胞中酶的催化特性相似,这表明在胎儿期和成年期红细胞酶可能仅存在一种形式。

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