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使用泼尼松和硫唑嘌呤成功治疗一名回缩性肠系膜膜炎患者。

Successful treatment of a patient with retractile mesenteritis with prednisone and azathioprine.

作者信息

Tytgat G N, Roozendaal K, Winter W, Esseveld M R

出版信息

Gastroenterology. 1980 Aug;79(2):352-6.

PMID:7399242
Abstract

A patient with retractile mesenteritis is discussed, who presented with a huge 15 X 15-cm inflammatory mass involving the root of the mesentery. Gradually the patient developed duodenal obstruction for which it was necessary to perform a gastroileostomy. Because of a relentless downhill course with fever, weight loss, general malaise, and fatigue, it was finally decided to treat the patient with prednisone and azathioprine. Upon institution of this treatment there was a steady, progressive clinical amelioration with disappearance of fever, improvement in laboratory findings, and gradual regression of the lesion until it became a well-delineated hard mass that was thought to be the end stage of fibrosis. Early trial with such a treatment, once the diagnosis is firmly established, should be considered.

摘要

讨论了一名患有回缩性肠系膜炎的患者,该患者出现了一个巨大的15×15厘米的炎性肿块,累及肠系膜根部。患者逐渐出现十二指肠梗阻,因此有必要进行胃回肠吻合术。由于病情持续恶化,伴有发热、体重减轻、全身不适和疲劳,最终决定用泼尼松和硫唑嘌呤治疗该患者。开始这种治疗后,临床症状稳步、逐渐改善,发热消失,实验室检查结果改善,病变逐渐消退,直至成为一个边界清晰的硬块,被认为是纤维化的终末期。一旦确诊,应考虑尽早试用这种治疗方法。

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Successful treatment of a patient with retractile mesenteritis with prednisone and azathioprine.使用泼尼松和硫唑嘌呤成功治疗一名回缩性肠系膜膜炎患者。
Gastroenterology. 1980 Aug;79(2):352-6.
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