Nyberg Lisa, Björk Jan, Björkdahl Peter, Ekberg Olle, Sjöberg Klas, Vigren Lina
Department of Medicine, Division of Gastroenterology, Hospital of Trelleborg, Trelleborg, Sweden.
Department of Gastroenterology and Hepatology, Karolinska University Hospital, Stockholm, Sweden.
BMC Gastroenterol. 2017 Jun 13;17(1):75. doi: 10.1186/s12876-017-0632-7.
Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course.
Patients observed due to idiopathic inflammation of the mesentery were identified. If SM could be verified histologically or MP radiologically, the patients were included in this descriptive retro perspective study.
Typical radiological changes were observed in 27 patients. A majority (23/27) of these patients had mild to moderate symptoms. This group with typical radiology was labelled MP. Four patients were included due to histologically verified disease but had uncharacteristic radiology involving multiple compartments of the abdomen. All four had marked systemic inflammation, fever and fluctuating radiologic findings. Three had severe disease with multiple hospitalisations and complications but responded promptly to corticosteroids. This group was denoted SM.
We have identified two subgroups of patients; firstly, MP with stable and characteristic radiologic changes and secondly SM with atypical radiology and a more aggressive clinical course. We propose that the term SM should be reserved for this latter condition.
硬化性系膜膜炎（SM）有时被用作肠系膜特发性炎症性疾病的统称。肠系膜脂膜炎（MP）是一种影像学表现，其与临床SM的关系尚未完全明确。本研究的目的是确定影像学表现与临床病程之间是否存在相关性。
确定因肠系膜特发性炎症而接受观察的患者。如果SM可通过组织学证实或MP通过影像学证实，则将这些患者纳入本描述性回顾性研究。
27例患者观察到典型的影像学改变。这些患者中的大多数（23/27）有轻度至中度症状。这组具有典型影像学表现的患者被标记为MP。4例患者因组织学证实的疾病而纳入，但有不典型的影像学表现，累及腹部多个腔隙。所有4例患者均有明显的全身炎症、发热和影像学表现波动。3例患者病情严重，多次住院并出现并发症，但对皮质类固醇反应迅速。这组患者被称为SM。
我们确定了两组患者亚群；第一组是具有稳定和特征性影像学改变的MP，第二组是具有不典型影像学表现和更具侵袭性临床病程的SM。我们建议将SM一词保留用于后一种情况。
