Sancho F G
Int Orthop. 1980;4(1):57-62. doi: 10.1007/BF00266604.
An experimental model of haemophilic arthropathy was developed in 12 growing dogs by anastomosing the popliteal artery to the joint cavity of the knee to produce haemarthrosis under considerable pressure. The dogs were sacrificed at intervals of one to eight weeks and the morphological and radiological changes found in the specimens mimicked those occurring in haemophilic arthropathy. In some of the animals total destruction of the articular cartilage and subchondral bone occurred. The significance of a high pressure haemarthrosis is discussed in relation to the development of changes found in haemophilic arthropathy.
通过将腘动脉吻合到膝关节腔以在相当大的压力下产生关节积血，在12只生长中的犬中建立了血友病性关节病的实验模型。每隔1至8周处死这些犬，并在标本中发现的形态学和放射学变化与血友病性关节病中发生的变化相似。在一些动物中，关节软骨和软骨下骨发生了完全破坏。结合血友病性关节病中发现的变化的发展，讨论了高压关节积血的意义。
