Tomilin N V, Zherebtsov S V
Mol Biol Rep. 1978 Oct 16;4(3):149-52. doi: 10.1007/BF00777515.
The filling of about one third of postreplication DNA gaps in u.v.-irradiated Micrococcus luteus ATCC 4698 is blocked by chloramphenicol (CA) added just before irradiation. Addition of CA 15 min after u.v.-irradiation does not prevent the complete repair of the gaps. U.v.-sensitive M. luteus mutants (ML 6 and ML 15) are identified as defective in different steps of inducible postreplication DNA repair (PRR). PRR in unexcising M. luteus strain G7 is accompanied by the transfer of about 20% of pyrimidine dimers from parental to daughter DNA strands, which indicates the existance of recombinational pathway of PRR. Recombinational PRR in M. luteus is not inhibited by CA.
在紫外线照射前即刻添加氯霉素（CA）可阻断紫外线照射的藤黄微球菌ATCC 4698中约三分之一的复制后DNA间隙的填补。紫外线照射15分钟后添加CA并不能阻止间隙的完全修复。紫外线敏感的藤黄微球菌突变体（ML 6和ML 15）在诱导性复制后DNA修复（PRR）的不同步骤中存在缺陷。未切除的藤黄微球菌菌株G7中的PRR伴随着约20%的嘧啶二聚体从亲代DNA链转移到子代DNA链，这表明存在PRR的重组途径。藤黄微球菌中的重组PRR不受CA抑制。
