Barnes M P
J Clin Pathol. 1980 May;33(5):481-3. doi: 10.1136/jcp.33.5.481.
The effect of laboratory reports, with restricted reporting of antibiotic information, on the prescribing of antimicrobials for urinary tract infection was assessed in a series of 250 patients. There was considerable prescribing of broad-spectrum antimicrobials, to which sensitivity was rarely reported, whether treatment was begun before or after the laboratory report was available, although they were used rather less in the latter situation. Of 147 patients with no evidence of bacteriuria, 26 (19%) received a full course of antimicrobial treatment. Of 49 asymptomatic catheterised patients with bacteriuria, 30 (61%) received antibiotics despite a recommendation to the contrary. The influence of laboratory reports is limited, and when the emergence and spread of resistant bacteria necessitates restraint with antimicrobials, restriction of antibiotic sensitivity reporting and recommendations by the laboratory may be insufficient.
在250例患者中评估了实验室报告（抗生素信息报告受限）对尿路感染抗菌药物处方的影响。广谱抗菌药物的使用相当普遍，无论治疗是在实验室报告出来之前还是之后开始，对其敏感性的报告都很少，尽管在后一种情况下使用得相对较少。在147例无菌尿证据的患者中，26例（19%）接受了全程抗菌治疗。在49例无症状的导尿菌尿患者中，30例（61%）尽管有相反的建议仍接受了抗生素治疗。实验室报告的影响有限，当耐药菌的出现和传播需要限制抗菌药物使用时，实验室对抗生素敏感性报告和建议可能是不够的。
