• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

2-脱氧-D-葡萄糖对大鼠下丘脑多单位活动的影响。

Effects of 2-deoxy-D-glucose on multi-unit activity of the hypothalamus in rats.

作者信息

Rabin B M, Miller D S

出版信息

J Neurosci Res. 1980;5(3):233-9. doi: 10.1002/jnr.490050308.

DOI:10.1002/jnr.490050308
PMID:7401200
Abstract

Multi-unit activity was recorded from the diencephalon of unanesthetized, immobilized female rats. Less than 50% of the recording sites in the hypothalamus showed changes in the level of multi-unit activity to changes in the level of glucose utilization induced by injection of 2-deoxy-D-glucose (2-DG). It was also not possible to specificy an area within the hypothalamus in which there was a concentration of recording sites which consistently responded to 2-DG. Relatively large amplitude, long duration changes in multi-unit activity levels were also observed in the optic tract, suggesting that 2-DG induced a widespread cellular metabolic response to glucoprivation which may not have been related to the regulation of feeding.

摘要

在未麻醉、固定的雌性大鼠的间脑中记录多单位活动。下丘脑内不到50%的记录位点显示,多单位活动水平随注射2-脱氧-D-葡萄糖(2-DG)诱导的葡萄糖利用水平变化而改变。也无法确定下丘脑内有一个集中的记录位点区域,这些位点始终对2-DG有反应。在视束中也观察到多单位活动水平相对较大幅度、持续时间较长的变化,这表明2-DG诱导了对葡萄糖剥夺的广泛细胞代谢反应,这可能与进食调节无关。

相似文献

1
Effects of 2-deoxy-D-glucose on multi-unit activity of the hypothalamus in rats.2-脱氧-D-葡萄糖对大鼠下丘脑多单位活动的影响。
J Neurosci Res. 1980;5(3):233-9. doi: 10.1002/jnr.490050308.
2
Bimodal effect of 2-deoxy-D-glucose on feeding.2-脱氧-D-葡萄糖对进食的双峰效应。
Tokai J Exp Clin Med. 1982 Jul;7(4):457-65.
3
Single neuron activity in the rat lateral hypothalamus during 2-deoxy-D-glucose induced and natural feeding behavior.2-脱氧-D-葡萄糖诱导的和自然进食行为期间大鼠外侧下丘脑的单神经元活动
Brain Res. 1985 Dec 16;359(1-2):1-9. doi: 10.1016/0006-8993(85)91406-4.
4
Feeding induced by intracerebroventricular 2-deoxy-D-glucose in the rat.脑室内注射2-脱氧-D-葡萄糖诱导大鼠进食。
Am J Physiol. 1975 Nov;229(5):1438-47. doi: 10.1152/ajplegacy.1975.229.5.1438.
5
Intracerebroventricular 2-DG causes feeding in the absence of other signs of glucoprivation.脑室内注射2-脱氧葡萄糖会在没有其他糖剥夺迹象的情况下引发进食。
Brain Res. 1980 Nov 24;202(1):229-33.
6
Ingestive behavior after intracerebral and intracerebroventricular infusions of glucose and 2-deoxy-D-glucose.脑内和脑室内注入葡萄糖和2-脱氧-D-葡萄糖后的摄食行为。
Am J Physiol. 1977 Sep;233(3):R127-33. doi: 10.1152/ajpregu.1977.233.3.R127.
7
Noradrenergic feeding system in monkey hypothalamus is altered by localized perfusion of glucose, insulin, 2-DG and eating.猴子下丘脑的去甲肾上腺素能进食系统会因葡萄糖、胰岛素、2-脱氧葡萄糖的局部灌注及进食而发生改变。
Pharmacol Biochem Behav. 1976 Oct;5(4):491-4. doi: 10.1016/0091-3057(76)90115-5.
8
Delayed response to 2-deoxy-D-glucose in hypothalamic obese rats.下丘脑肥胖大鼠对2-脱氧-D-葡萄糖的反应延迟。
Pharmacol Biochem Behav. 1978 Mar;8(3):259-62. doi: 10.1016/0091-3057(78)90313-1.
9
Hypothalamic norepinephrine in the rat during feeding and push-pull perfusion with glucose, 2-DG, or insulin.喂食期间以及用葡萄糖、2-脱氧葡萄糖或胰岛素进行推挽灌注时大鼠下丘脑去甲肾上腺素的变化
Am J Physiol. 1979 May;236(5):R312-21. doi: 10.1152/ajpregu.1979.236.5.R312.
10
[14C]Deoxyglucose mapping of first-order projections activated by stimulation of lateral hypothalamic sites eliciting gnawing, eating, and drinking in rats.[14C]脱氧葡萄糖对大鼠下丘脑外侧部位刺激引发啃咬、进食和饮水时激活的一级投射的映射。
J Comp Neurol. 1980 Dec 1;194(3):617-38. doi: 10.1002/cne.901940309.