Zulley J
Sleep. 1980;2(4):377-89.
One hundred thirty sleep episodes of 6 subjects, living on a natural 24 hr day, were compared with 116 sleep times of the same subjects living isolated from external time cues. The polygraphic sleep recordings were analyzed for the distribution of REM sleep under both conditions. Additionally, the relationship between body temperature and REM sleep was analyzed by comparing sleep episodes in which the temperature minimum occurred early in the sleep episode with those in which there was a late temperature minimum. The results show that there is more REM sleep in the beginning of sleep in sleep episodes of free-running rhythms as compared to sleep episodes of entrained 24 hr rhythms. This higher amount of REM sleep is due to a longer first REM episode and shorter first NREM episodes. The comparison of the sleep episodes that differ in the position of the temperature minimum shows similar differences, i.e., more REM sleep in the beginning of sleep episodes in which the temperature minimum occurs earlier as compared to episodes in which the temperature minimum occurs later. It was hypothesized that the amount of REM sleep depends on the phase relationship between sleep and the circadian temperature cycle. From this point of view, the difference in the distribution of REM sleep in the entrained 24 hr rhythm, on the one hand, and the free-running rhythm, on the other hand, can be explained by the different courses of body temperature during sleep. That only the first REM episode is influenced by circadian parameters may indicate an exceptional role for this REM episode in contrast to the following episodes.
对6名生活在自然24小时昼夜节律下的受试者的130次睡眠时段，与同6名受试者在隔离外界时间线索情况下的116次睡眠时间进行了比较。分析了两种条件下多导睡眠图记录中快速眼动睡眠（REM睡眠）的分布情况。此外，通过比较体温最低点出现在睡眠时段早期的睡眠时段与体温最低点出现较晚的睡眠时段，分析了体温与REM睡眠之间的关系。结果显示，与24小时同步节律的睡眠时段相比，自由运行节律的睡眠时段在睡眠开始时存在更多的REM睡眠。REM睡眠量的增加是由于首个REM时段更长且首个非快速眼动睡眠（NREM）时段更短。对体温最低点位置不同的睡眠时段进行比较，结果显示出类似差异，即与体温最低点出现较晚的时段相比，体温最低点出现较早的睡眠时段在睡眠开始时存在更多的REM睡眠。据推测，REM睡眠量取决于睡眠与昼夜体温周期之间的相位关系。从这一角度来看，一方面，24小时同步节律中REM睡眠分布的差异，与另一方面自由运行节律中REM睡眠分布的差异，可以通过睡眠期间体温的不同变化过程来解释。只有首个REM时段受昼夜节律参数影响，这可能表明该REM时段与后续时段相比具有特殊作用。
