Rousset J P, Jami J, Dubois P, Avilès D, Ritz E
Somatic Cell Genet. 1980 May;6(3):419-33. doi: 10.1007/BF01542793.
Hybrids between PCC4-aza 1 teratocarcinoma cells and either thymus cells (PcT and RPcT hybrids) or Lc lymphocytic leukemia cells (PcLc hybrids) are carcinoma cells and when injected into hosts they produce tumors which are teratocarcinomas. PcT and RPcT hybrids) or Lc lymphocytic leukemia cells (PcLc hybrids) are carcinoma cells and when injected into hosts they produce tumors which are teratocarcinomas. PcT and RPcT hybrid tumors are well differentiated and include a large variety of somatic tissues. In most PcLc tumors, neuroectoderm differentiation is predomonant. Like the PCC4 parental cells, PcT, RPcT, and PcLc hybrids carry F9 embryonic antigens and do not express perceptible amounts of H-2 alloantigens. Nonexpression of the H-2d haplotype of the thymus cell parent in PcT hybrids is not due to the loss of chromosome 17 which carried the major histocompatibility complex.
PCC4 - aza 1畸胎瘤细胞与胸腺细胞（PcT和RPcT杂种细胞）或Lc淋巴细胞白血病细胞（PcLc杂种细胞）形成的杂种细胞是癌细胞，将其注入宿主后会产生畸胎瘤。PcT和RPcT杂种细胞）或Lc淋巴细胞白血病细胞（PcLc杂种细胞）是癌细胞，将其注入宿主后会产生畸胎瘤。PcT和RPcT杂种瘤分化良好，包含多种体细胞组织。在大多数PcLc肿瘤中，神经外胚层分化占主导。与PCC4亲代细胞一样，PcT、RPcT和PcLc杂种细胞携带F9胚胎抗原，且不表达可察觉量的H - 2同种异体抗原。胸腺细胞亲代的H - 2d单倍型在PcT杂种细胞中不表达，并非由于携带主要组织相容性复合体的17号染色体缺失所致。
