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生物类黄酮对佐剂性关节炎中羟脯氨酸、羟赖氨酰糖苷和氨基己糖尿排泄的影响。

Effect of bioflavonoids on the urinary excretion of hydroxyproline, hydroxylysyl glycosides and hexosamine in adjuvant arthritis.

作者信息

Rao C N, Rao V H

出版信息

Ital J Biochem. 1980 Mar-Apr;29(2):89-101.

PMID:7410047
Abstract

The effects of (+)--Catechin (AC) and 0--(beta hydroxyethyl) rutosides (HR) on the urinary collagen metabolites were studied up to 49 days in rats with adjuvant-induced arthritis. The elevated levels of urinary total, non-dialysable and dialysable hydroxyproline, hydroxylysyl glycosides and total hexosamine in the arthritic animals were found to be slightly decreased in the acute phase and significantly decreased in the chronic phase of the disease due to the administration of bioflavonoids. Of the two bioflavonoids tests, CA was found to afford more protective action than HR.

摘要

在佐剂诱导性关节炎大鼠中,研究了(+)-儿茶素(AC)和羟乙基芦丁(HR)对尿胶原代谢产物的影响,为期49天。发现由于给予生物类黄酮,关节炎动物尿中总羟脯氨酸、非透析性和透析性羟脯氨酸、羟赖氨酰糖苷和总己糖胺水平升高,在疾病急性期略有下降,在慢性期显著下降。在两种生物类黄酮测试中,发现CA比HR具有更强的保护作用。

相似文献

1
Effect of bioflavonoids on the urinary excretion of hydroxyproline, hydroxylysyl glycosides and hexosamine in adjuvant arthritis.生物类黄酮对佐剂性关节炎中羟脯氨酸、羟赖氨酰糖苷和氨基己糖尿排泄的影响。
Ital J Biochem. 1980 Mar-Apr;29(2):89-101.
2
Urinary excretion of hydroxyproline and hydroxylysyl glycosides in adjuvant-induced arthritis.佐剂诱导性关节炎中羟脯氨酸和羟赖氨酰糖苷的尿排泄情况
Ital J Biochem. 1979 May-Jun;28(3):173-82.
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Influence of bioflavonoids on the collagen metabolism in rats with adjuvant induced arthritis.
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4
Urinary excretion of connective tissue metabolites under the influence of a new non-steroidal anti-inflammatory agent in adjuvant induced arthritis.新型非甾体抗炎药对佐剂诱导性关节炎结缔组织代谢产物尿排泄的影响
Agents Actions. 1987 Oct;22(1-2):99-105. doi: 10.1007/BF01968824.
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Urinary excretion of collagen metabolites in protein malnutrition.蛋白质营养不良时胶原蛋白代谢产物的尿排泄情况。
J Clin Chem Clin Biochem. 1980 May;18(5):287-91. doi: 10.1515/cclm.1980.18.5.287.
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Variations in human urinary O-hydroxylysyl glycoside levels and their relationship to collagen metabolism.人类尿液中O-羟赖氨酸糖苷水平的变化及其与胶原蛋白代谢的关系。
J Clin Invest. 1970 Aug;49(8):1497-509. doi: 10.1172/JCI106367.
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引用本文的文献

1
Urinary excretion of connective tissue metabolites under the influence of a new non-steroidal anti-inflammatory agent in adjuvant induced arthritis.新型非甾体抗炎药对佐剂诱导性关节炎结缔组织代谢产物尿排泄的影响
Agents Actions. 1987 Oct;22(1-2):99-105. doi: 10.1007/BF01968824.