Wakisaka Y, Koizumi K, Nishimoto Y, Kobayashi M, Tsuji N
J Antibiot (Tokyo). 1980 Jul;33(7):695-704. doi: 10.7164/antibiotics.33.695.
A newly isolated bacterium which produces antibacterial substances as below was taxonomically characterized and identified with Corynebacterium equi. The major antibiotic produced was determined to be hygromycin by direct comparison. The minor component, newly named epihygromycin was proved to be an epimer of hygromycin by spectrosocopic evidences and by chemical conversions. The presence of epihygromycin in the metabolites of Streptomyces noboritoensis (reported to be a hygromycin producer) was also observed.
对一株新分离出的、能产生如下抗菌物质的细菌进行了分类学特征分析，并鉴定为马棒状杆菌。通过直接比较确定主要产生的抗生素为潮霉素。次要成分新命名为表潮霉素，通过光谱证据和化学转化证明它是潮霉素的差向异构体。在诺堀链霉菌（据报道是潮霉素产生菌）的代谢产物中也观察到了表潮霉素的存在。
