Van Wagoner S, Risser J, Moyer M, Lasky D
Percept Mot Skills. 1980 Jun;50(3 Pt 2):1119-24. doi: 10.2466/pms.1980.50.3c.1119.
Shape discrimination learning by four groups of 150-day-old Sprague-Dawley rats was studied. The groups were the offspring of mothers on the following schedules: (1) prenatal and postnatal methadone, (2) prenatal methadone and postnatal saline, (3) prenatal and postnatal methadone, and (4) prenatal and postnatal saline. The hypothesis investigated was that the methadone groups would show a deficit in learning when compared to the saline-control group. This hypothesis was upheld for the prenatal methadone group and the postnatal methadone group.
对四组150日龄的斯普拉格-道利大鼠的形状辨别学习进行了研究。这些组是处于以下喂养计划下的母鼠的后代：（1）产前和产后均使用美沙酮，（2）产前使用美沙酮，产后使用生理盐水，（3）产前和产后均使用美沙酮，以及（4）产前和产后均使用生理盐水。所研究的假设是，与生理盐水对照组相比，美沙酮组在学习方面会表现出缺陷。该假设在产前美沙酮组和产后美沙酮组中得到了证实。
