Pedraz C, Lorente F, Pedraz M J, Salazar Villalobos V
An Esp Pediatr. 1980 Jul;13(7):571-6.
Development of human C. system was studied by quantification of total serum hemolytical activity (CH50) and individual levels of C3, C4 and C5 in full term newborns. Comparison of results in newborn infants and their mothers sera is made. The ratios of neonatal-maternal sera concentrations were CH50, 0.29; C3, 0.61; C4, 0.51, and C5, 0.63. Serum concentrations of C3 and C4 reached maternal concentrations at twelve months of age. Serum concentrations of C4 and CH50 reached maternal levels at six months of age.
通过对足月新生儿血清总溶血活性(CH50)以及C3、C4和C5的个体水平进行定量研究人类补体系统的发育情况。对新生儿及其母亲血清的结果进行了比较。新生儿与母亲血清浓度的比值分别为:CH50为0.29;C3为0.61;C4为0.51;C5为0.63。C3和C4的血清浓度在12个月大时达到母亲的浓度水平。C4和CH50的血清浓度在6个月大时达到母亲的水平。