甲型流感病毒株Nav2、Nav3和Nav6神经氨酸酶的遗传相关性。
Genetic relatedness of the neuramindase of influenza A strains Nav2, Nav3, and Nav6.
作者信息
Scholtissek C, Rott R, Lvov D K, Myasnikova I A
出版信息
Arch Virol. 1980;65(3-4):325-8. doi: 10.1007/BF01314548.
By molecular hybridization and by neuraminidase inhibition tests it is shown that all influenza A strains tested carrying an Nav3 or Nav2 neuraminidase (NA) are genetically highly related in their NA genes and cross-react serologically with specific antineuraminidase sera. The Nav6 strains exhibit a very low RNase protection after hybridization and do not cross-react serologically with Nav2 or Nav3 strains. Thus, the Nav2 and Nav3 strains comprise one group which is distinct from that of Nav6 strains.
通过分子杂交和神经氨酸酶抑制试验表明，所有携带Nav3或Nav2神经氨酸酶（NA）的甲型流感病毒株在其NA基因上具有高度的遗传相关性，并且与特异性抗神经氨酸酶血清发生血清学交叉反应。Nav6病毒株在杂交后表现出非常低的核糖核酸酶保护作用，并且与Nav2或Nav3病毒株不发生血清学交叉反应。因此，Nav2和Nav3病毒株组成一组，与Nav6病毒株不同。
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