Mutz I D, Urban C E
Wien Klin Wochenschr. 1978 Dec 22;90(24):867-70.
Eight children with state III or IV neuroblastoma were treated with courses of chemotherapy consisting of nitrogen mustard (6 mg/m2), vincristine (2 X 1.5 mg/m2), doxorubicin (40 mg/m2) and dimethyl-triazeno-imidazolecarboxamide (850 mg/m2) every three weeks. Three children died after a median survival of 8 (+/-5) months. Five children (62%) have now survived for a medium duration of 21 (+/-16) months without clinical evidence of disease. These results are far better than previously-achieved survival rates at our department.
八名患有Ⅲ期或Ⅳ期神经母细胞瘤的儿童接受了化疗疗程，每三周使用一次化疗药物，包括氮芥（6毫克/平方米）、长春新碱（2×1.5毫克/平方米）、阿霉素（40毫克/平方米）和二甲基三氮烯咪唑甲酰胺（850毫克/平方米）。三名儿童在中位生存期为8（±5）个月后死亡。五名儿童（62%）目前已存活21（±16）个月，且无疾病临床证据。这些结果远优于我们科室之前取得的生存率。
