Touwen B C, Huisjes H J, Jurgens-van der Zee A D, Bierman-van Eendenburg M E, Smrkovsky M, Olinga A A
Early Hum Dev. 1980 Sep;4(3):207-28. doi: 10.1016/0378-3782(80)90027-4.
In order to increase understanding of the origin of neonatal neurological morbidity, the relationship between the obstetrical and neonatal neurological conditions was studied in a 3-year cohort containing 3162 singleton infants. The infants were neurologically examined at term age according to the technique described by Prechtl. Obstetrical data were documented extensively. Prechtl's optimality concept was applied in the analysis. A statistically significant relationship was found between the obstetrical and neonatal neurological optimality scores. There was no sex difference in the obstetrical optimality, whereas there was in the neurological optimality, to the advantage of the girls. It could be shown that obstetrical conditions such as acidemia, preterm birth and intrauterine growth retardation have a stronger relationship to neurological morbidity when the accompanying obstetrical optimality is lower. In obstetrical practice the application of the optimality concept to obstetrical and neurological data is a helpful complementary refinement.
为了增进对新生儿神经疾病发病根源的理解，我们在一个包含3162名单胎婴儿的3年队列中研究了产科情况与新生儿神经状况之间的关系。根据Prechtl所描述的技术，在足月时对婴儿进行神经学检查。广泛记录产科数据。分析中应用了Prechtl的最优性概念。在产科最优性评分与新生儿神经最优性评分之间发现了具有统计学意义的关系。产科最优性方面不存在性别差异，而在神经最优性方面存在性别差异，女孩占优势。可以表明，当伴随的产科最优性较低时，诸如酸血症、早产和宫内生长迟缓等产科情况与神经疾病的关系更为密切。在产科实践中，将最优性概念应用于产科和神经学数据是一种有益的补充完善。
