Berg T, Nordvall S L, Lanner A
Int Arch Allergy Appl Immunol. 1980;63(3):266-74.
A purified freeze-dried preparation of timothy pollen was compared with a crude extract in RAST, skin tests, conjunctival provocation tests and desensitization treatment. In 48 children with grass pollen allergy a thorough allergological investigation was performed, using the two allergen preparations in different tests. The purified preparation contained relevant allergens, as judged from the good agreement between the two extracts in prick and provocation tests. The freeze-dried purified extract had good storage stability. Desensitization treatment was found to have a significant effect, as judged by repeated prick and provocation tests with both extracts. The effect of the desensitization treatment was at least as good in the children treated with the purified preparation as in those treated with the crude extract.
将提纯的冻干梯牧草花粉制剂与粗提取物在放射性变应原吸附试验（RAST）、皮肤试验、结膜激发试验及脱敏治疗中进行比较。对48名对草花粉过敏的儿童进行了全面的变应性学调查，在不同试验中使用这两种变应原制剂。从两种提取物在点刺试验和激发试验中的良好一致性判断，提纯制剂含有相关变应原。冻干提纯提取物具有良好的储存稳定性。通过对两种提取物反复进行点刺试验和激发试验判断，发现脱敏治疗有显著效果。用提纯制剂治疗的儿童，脱敏治疗效果至少与用粗提取物治疗的儿童一样好。
