Wahi R S, Chansouria J P, Udupa K N
J Clin Endocrinol Metab. 1980 Oct;51(4):934-5. doi: 10.1210/jcem-51-4-934.
Plasma epinephrine and norepinephrine levels were measured in four cases of short term hypothyroidism which developed after parturition. For comparison, six patients with idiopathic hypothyroidism were included in the study. Hypothyroidism was confirmed by clinical evaluation and tests of thyroid function, viz. serum T3, T4, free T4, and TSH. In all patients with idiopathic hyperthyroidism, epinephrine levels were normal and norepinephrine levels were significantly elevated. In the four patients with short term hypothyroidism, normal levels of epinephrine as well as norepinephrine were observed. Circulating thyroid hormone levels start increasing after 6--9 months in patients with short term hypothyroidism reaching euthyroid levels after 1 yr. The present results indicate that plasma norepinephrine concentrations in hypothyroidism seem to be significantly increased only after a lag period of some 6--9 months.
对4例产后发生的短期甲状腺功能减退患者测定了血浆肾上腺素和去甲肾上腺素水平。为作比较,研究纳入了6例特发性甲状腺功能减退患者。甲状腺功能减退通过临床评估和甲状腺功能检查得以确诊,即血清T3、T4、游离T4和促甲状腺激素(TSH)。在所有特发性甲状腺功能减退患者中,肾上腺素水平正常而去甲肾上腺素水平显著升高。在4例短期甲状腺功能减退患者中,观察到肾上腺素和去甲肾上腺素水平均正常。短期甲状腺功能减退患者的循环甲状腺激素水平在6 - 9个月后开始升高,1年后达到甲状腺功能正常水平。目前的结果表明,甲状腺功能减退患者血浆去甲肾上腺素浓度似乎仅在约6 - 9个月的延迟期后才会显著升高。