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短期甲状腺功能减退时去甲肾上腺素水平正常。

Normal levels of norepinephrine in short term hypothyroidism.

作者信息

Wahi R S, Chansouria J P, Udupa K N

出版信息

J Clin Endocrinol Metab. 1980 Oct;51(4):934-5. doi: 10.1210/jcem-51-4-934.

DOI:10.1210/jcem-51-4-934
PMID:7419674
Abstract

Plasma epinephrine and norepinephrine levels were measured in four cases of short term hypothyroidism which developed after parturition. For comparison, six patients with idiopathic hypothyroidism were included in the study. Hypothyroidism was confirmed by clinical evaluation and tests of thyroid function, viz. serum T3, T4, free T4, and TSH. In all patients with idiopathic hyperthyroidism, epinephrine levels were normal and norepinephrine levels were significantly elevated. In the four patients with short term hypothyroidism, normal levels of epinephrine as well as norepinephrine were observed. Circulating thyroid hormone levels start increasing after 6--9 months in patients with short term hypothyroidism reaching euthyroid levels after 1 yr. The present results indicate that plasma norepinephrine concentrations in hypothyroidism seem to be significantly increased only after a lag period of some 6--9 months.

摘要

对4例产后发生的短期甲状腺功能减退患者测定了血浆肾上腺素和去甲肾上腺素水平。为作比较,研究纳入了6例特发性甲状腺功能减退患者。甲状腺功能减退通过临床评估和甲状腺功能检查得以确诊,即血清T3、T4、游离T4和促甲状腺激素(TSH)。在所有特发性甲状腺功能减退患者中,肾上腺素水平正常而去甲肾上腺素水平显著升高。在4例短期甲状腺功能减退患者中,观察到肾上腺素和去甲肾上腺素水平均正常。短期甲状腺功能减退患者的循环甲状腺激素水平在6 - 9个月后开始升高,1年后达到甲状腺功能正常水平。目前的结果表明,甲状腺功能减退患者血浆去甲肾上腺素浓度似乎仅在约6 - 9个月的延迟期后才会显著升高。

相似文献

1
Normal levels of norepinephrine in short term hypothyroidism.短期甲状腺功能减退时去甲肾上腺素水平正常。
J Clin Endocrinol Metab. 1980 Oct;51(4):934-5. doi: 10.1210/jcem-51-4-934.
2
Catecholamine metabolism in thyroid disease. II. Norepinephrine secretion rate in hyperthyroidism and hypothyroidism.甲状腺疾病中的儿茶酚胺代谢。II. 甲状腺功能亢进和减退时去甲肾上腺素分泌率
J Clin Endocrinol Metab. 1977 Jun;44(6):1185-9. doi: 10.1210/jcem-44-6-1185.
3
The relationship of serum thyrotropin (TSH) to the thyroid hormones after oral TSH-releasing hormone in patients with preclinical hypothyroidism.亚临床甲状腺功能减退患者口服促甲状腺激素释放激素后血清促甲状腺激素(TSH)与甲状腺激素的关系。
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Changes in serum triiodothyronine, thyroxine, and thyrotropin during treatment with thyroxine in severe primary hypothyroidism.重度原发性甲状腺功能减退症患者在接受甲状腺素治疗期间血清三碘甲状腺原氨酸、甲状腺素和促甲状腺激素的变化。
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Effect of thyroid status and paraventricular area lesions on the release of thyrotropin-releasing hormone and catecholamines into hypophysial portal blood.甲状腺状态和室旁区域损伤对促甲状腺激素释放激素和儿茶酚胺释放到垂体门脉血液中的影响。
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Serum levels of thyrotropin, prolactin, growth hormone, triiodothyronine and thyroxine after oral administration of thyrotropin releasing hormone in hypothyroid and hyperthyroid patients.甲状腺功能减退和甲状腺功能亢进患者口服促甲状腺激素释放激素后血清促甲状腺激素、催乳素、生长激素、三碘甲状腺原氨酸和甲状腺素水平。
Endokrinologie. 1976;68(2):175-82.
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Measurement of serum total thyroxine, triiodothyronine, free thyroxine, and thyrotropin concentrations for diagnosis of hypothyroidism in dogs.测定犬血清总甲状腺素、三碘甲状腺原氨酸、游离甲状腺素和促甲状腺激素浓度以诊断犬甲状腺功能减退症。
J Am Vet Med Assoc. 1997 Dec 1;211(11):1396-402.

引用本文的文献

1
Effects of thyroid replacement therapy on catecholamine plasma levels.甲状腺替代疗法对血浆儿茶酚胺水平的影响。
J Endocrinol Invest. 1983 Aug;6(4):307-9. doi: 10.1007/BF03347596.
2
Pathophysiology of sympathoadrenal system.交感肾上腺系统的病理生理学
J Endocrinol Invest. 1988 Dec;11(11):817-29. doi: 10.1007/BF03350236.