帕金森病伴发的痴呆：一项遗传学研究。
Dementia associated with Parkinson's disease: a genetic study.
作者信息
Heston L L
出版信息
J Neurol Neurosurg Psychiatry. 1980 Sep;43(9):846-8. doi: 10.1136/jnnp.43.9.846.
Abstract
Relatives of 12 probands who had severe dementia associated with Parkinson's disease were studied. A high risk for Parkinson's disease was found among relatives but only one instance of dementia. The high risk to relatives and the dementia of the probands appeared to be related to the overall severity of the Parkinsonian illness.
摘要
对12名患有与帕金森病相关的严重痴呆症的先证者的亲属进行了研究。在亲属中发现帕金森病的高风险，但只有一例痴呆症。亲属的高风险和先证者的痴呆症似乎与帕金森病的总体严重程度有关。
相似文献
1
Dementia associated with Parkinson's disease: a genetic study.帕金森病伴发的痴呆：一项遗传学研究。
J Neurol Neurosurg Psychiatry. 1980 Sep;43(9):846-8. doi: 10.1136/jnnp.43.9.846.
2
Associations between family history of Parkinson's disease and dementia and risk of dementia in Parkinson's disease: A community-based, longitudinal study.帕金森病家族史与痴呆症之间的关联以及帕金森病患者患痴呆症的风险：一项基于社区的纵向研究。
Mov Disord. 2006 Dec;21(12):2170-4. doi: 10.1002/mds.21144.
3
Apolipoprotein E genotypes in Parkinson's disease with and without dementia.患帕金森病且伴有或不伴有痴呆症患者的载脂蛋白E基因型
Ann Neurol. 1995 Feb;37(2):242-5. doi: 10.1002/ana.410370215.
4
5
Mutations in glucocerebrosidase are a major genetic risk factor for Parkinson's disease and increase susceptibility to dementia in a Flanders-Belgian cohort.葡萄糖脑苷脂酶突变是帕金森病的主要遗传风险因素，在一个佛兰德 - 比利时队列中会增加患痴呆症的易感性。
Neurosci Lett. 2016 Aug 26;629:160-164. doi: 10.1016/j.neulet.2016.07.008. Epub 2016 Jul 7.
6
Are genetic and sporadic Parkinson's disease patients equally susceptible to develop dementia?遗传性和散发性帕金森病患者发生痴呆的易感性是否相同？
J Neurol Sci. 2010 Feb 15;289(1-2):23-6. doi: 10.1016/j.jns.2009.08.015. Epub 2009 Sep 8.
7
A study of familial aggregation of depression, dementia and Parkinson's disease.一项关于抑郁症、痴呆症和帕金森病家族聚集性的研究。
Eur J Epidemiol. 1998 Apr;14(3):233-8. doi: 10.1023/a:1007488902983.
8
History of dementia and Parkinson's disease in 1st-degree relatives of patients with Alzheimer's disease.阿尔茨海默病患者一级亲属中痴呆症和帕金森病的病史。
Neurology. 1989 Dec;39(12):1589-92. doi: 10.1212/wnl.39.12.1589.
9
C9ORF72 intermediate repeat expansion in patients affected by atypical parkinsonian syndromes or Parkinson's disease complicated by psychosis or dementia in a Sardinian population.撒丁岛人群中受非典型帕金森综合征或合并精神病或痴呆的帕金森病影响的患者的C9ORF72中间重复序列扩增
J Neurol. 2015 Nov;262(11):2498-503. doi: 10.1007/s00415-015-7873-6. Epub 2015 Aug 15.
10
Clinical and neuroimaging features of patient with early-onset Parkinson's disease with dementia carrying SNCA p.G51D mutation.携带SNCA p.G51D突变的早发性帕金森病伴痴呆患者的临床和神经影像学特征
Parkinsonism Relat Disord. 2014 Feb;20(2):262-4. doi: 10.1016/j.parkreldis.2013.11.008. Epub 2013 Nov 20.
引用本文的文献
1
The Relationship between Physical Exercise and Cognitive Function in Korean Middle Aged and Elderly Adults without Dementia.《不患有痴呆的韩国中老年人群体中，体育锻炼与认知功能的关系》。
Int J Environ Res Public Health. 2020 Nov 27;17(23):8821. doi: 10.3390/ijerph17238821.
2
Somatostatin-like immunoreactivity in the cerebrospinal fluid of patients with Parkinson's disease and its relation to dementia.帕金森病患者脑脊液中生长抑素样免疫反应性及其与痴呆的关系。
J Neurol Neurosurg Psychiatry. 1986 Dec;49(12):1374-7. doi: 10.1136/jnnp.49.12.1374.
3
A comparative technetium 99m hexamethylpropylene amine oxime SPET study in different types of dementia.不同类型痴呆的锝99m六甲基丙烯胺肟单光子发射计算机断层扫描对比研究。
Eur J Nucl Med. 1991;18(1):3-11. doi: 10.1007/BF00177677.
本文引用的文献
1
Parkinsonism: onset, progression and mortality.帕金森症：发病、进展与死亡率
Neurology. 1967 May;17(5):427-42. doi: 10.1212/wnl.17.5.427.
2
The prevalence, natural history and dementia of Parkinson's disease.帕金森病的患病率、自然史与痴呆
Brain. 1966 Sep;89(3):429-48. doi: 10.1093/brain/89.3.429.
3
Parkinson's disease. Genetic analysis and evidence of a multifactorial etiology.
Mayo Clin Proc. 1973 Jul;48(7):465-75.
4
Parkinson's disease. A genetic study.帕金森病。一项遗传学研究。
Brain. 1973 Sep;96(3):495-506. doi: 10.1093/brain/96.3.495.
5
Psychiatric illness in relatives of patients with Parkinson's disease: a preliminary report.
Am J Psychiatry. 1977 Apr;134(4):443-4. doi: 10.1176/ajp.134.4.443.
6
The distribution of ancestral secondary cases in Parkinson's disease.
Clin Genet. 1977 Mar;11(3):189-92. doi: 10.1111/j.1399-0004.1977.tb01298.x.
7
The genetics of Alzheimer's disease: associations with hematologic malignancy and Down's syndrome.阿尔茨海默病的遗传学：与血液系统恶性肿瘤和唐氏综合征的关联。
Arch Gen Psychiatry. 1977 Aug;34(8):976-81. doi: 10.1001/archpsyc.1977.01770200114017.
Zotero 插件