Postnov Iu V, Orlov S N, Pokudin N I
Kardiologiia. 1980 Sep;20(9):69-72.
Peripheral immunosympathectomy by the nerve growth factor antiserum treatment prevents the development of spontaneous hypertension in rats. Both spontaneously hypertensive intact (sham-treated) rats and animals previously subjected to peripheral immunosympathectomy, however, exhibit a change in intracellular calcium distribution in the adipose tissue (an increase content of the most rapidly exchangeable part of intracellular calcium). It may therefore be concluded that the change in the membrane control over intracellular calcium in the adipose tissue of spontaneously hypertensive rats is not conditioned by the influence of enhanced sympathetic activity.
用神经生长因子抗血清治疗进行外周免疫交感神经切除术可预防大鼠自发性高血压的发展。然而，自发性高血压未处理（假手术）大鼠和先前接受外周免疫交感神经切除术的动物，其脂肪组织中的细胞内钙分布均发生了变化（细胞内钙最快速可交换部分的含量增加）。因此可以得出结论，自发性高血压大鼠脂肪组织中对细胞内钙的膜控制变化并非由增强的交感神经活动的影响所致。
