Emmett-Oglesby M W, Taylor K E, Dafter R E
Pharmacol Biochem Behav. 1980 Sep;13(3):467-70. doi: 10.1016/0091-3057(80)90257-9.
Rats were trained to press a bar with water reinforcement under a variable interval 15-sec (VI 15), variable interval 15-sec signalled-reinforcement (VI SD), or a differential-reinforcement-of-low-rate 10-sec (DRL 10) schedule. Methylphenidate (MP) had little effect on response rates or reinforcements-earned in the VI 15 group. However, MP increased response rates in a dose-related manner in the VI SD and the DRL 10 groups. These findings and additional results reported in the literature suggest that signalled reinforcement does not necessarily antagonize the rate-increasing effects of the amphetamine-type drugs.
大鼠在可变间隔15秒（VI 15）、可变间隔15秒信号强化（VI SD）或低速率差异强化10秒（DRL 10）的时间表下，接受以水为强化物按压杠杆的训练。哌醋甲酯（MP）对VI 15组的反应率或获得的强化物影响很小。然而，MP在VI SD组和DRL 10组中以剂量相关的方式提高了反应率。这些发现以及文献中报道的其他结果表明，信号强化不一定会拮抗苯丙胺类药物的速率增加效应。
