Bouza E, Dominguez A, Meseguer M, Buzon L, Boixeda D, Revillo M J, de Rafael L, Martinez-Beltran J
Am J Clin Pathol. 1980 Oct;74(4):404-9. doi: 10.1093/ajcp/74.4.404.
Human Yersinia enterocolitica septicemia is an uncommon condition. Four new cases are reported here and a review is made of 51 others taken from medical literature. Septicemia caused by this microorganism occurs more frequently in the young and in the elderly, and usually involves patients havig previous liver or blood disorders, diabetes mellitus, and other debilitating diseases. Clinically it is indistinguishable from sepsis caused by other organisms of Enterobacteriaceae, but it is important that the clinician bear its existence in mind, since Yersinia enterocolitica strains are usually resistant to beta-lactam antibiotics, whereas they are susceptible to the aminoglycosides and co-trimoxazole, among others. Susceptibilities in the blood isolates from our patients, and in another ten fecal isolates from eight other patients showed the previously described pattern. Our isolates, however, were all susceptible to the new cephalosporins, cefamandole and cefoxitin, and to the experimental ones, HR-756, T-1551, and Ly-127.935.
人类小肠结肠炎耶尔森菌败血症是一种罕见病症。本文报告了4例新病例，并对医学文献中另外51例病例进行了综述。这种微生物引起的败血症在年轻人和老年人中更为常见，通常累及先前有肝脏或血液疾病、糖尿病及其他衰弱性疾病的患者。临床上，它与由其他肠杆菌科细菌引起的败血症难以区分，但临床医生必须牢记其存在，因为小肠结肠炎耶尔森菌菌株通常对β-内酰胺类抗生素耐药，而对氨基糖苷类和复方新诺明等敏感。我们患者血液分离株以及另外8例患者的10份粪便分离株的药敏情况显示出上述模式。然而，我们的分离株对新型头孢菌素头孢孟多和头孢西丁以及实验性药物HR-756、T-1551和Ly-127.935均敏感。
