Beliaeva I D, Rodionov V M
Biull Eksp Biol Med. 1980 Oct;90(10):474-6.
In the course of AH22A development the size of G2 subpopulations (G2 period cell of the mitotic cycle) changes relatively little for the most part, slightly decreasing in the terminal stage. Five days before the terminal stage of AH22A the cell subpopulation was found to be in the reversible resting R2 stage (the population egressed from the mitotic cycle in G2 period). The size of the population increased with tumor growth. In the terminal stage, however, its size was insignificant (47%). Therefore, it is not possible to prove that cells accumulate in considerable amounts in the reversible resting R2 stage. This circumstance and a decrease in the size of G2 subpopulation and cell population in advanced tumors during the reversible resting R2 stage evidence that the latter one is of a relatively short duration in the course of cell egress from G2 period of the mitotic cycle in the irreversible resting stage.
在AH22A的发育过程中，G2亚群（有丝分裂周期的G2期细胞）的大小在大部分时间变化相对较小，在末期略有下降。在AH22A末期前五天，发现细胞亚群处于可逆静止的R2期（该群体在G2期退出有丝分裂周期）。该群体的大小随肿瘤生长而增加。然而，在末期，其大小微不足道（47%）。因此，无法证明细胞在可逆静止的R2期大量积累。这种情况以及在晚期肿瘤的可逆静止R2期G2亚群和细胞群体大小的减少表明，在细胞从有丝分裂周期的G2期进入不可逆静止期的过程中，后者持续时间相对较短。
