Ivleva T S, Beliaeva I D
Biull Eksp Biol Med. 1978 Oct;86(10):479-82.
The authors studied growth peculiarities of the ascitic hepatoma 22A at the terminal stage of development. As shown by the autoradiography method, some of the cells could be at the G1-period or at the R1-period for 2 or even 4 days; the average duration of the G2-period constituted 16 hours. 55--60% of the cells were at the much prolonged G1- and R1-period, 7%--at the S-period, and 9%--at the G2-period. The rest 25--30% of cells apparently leave the mitotic cycle irreversibly since they take no part in proliferation after the division stimulation.
作者研究了腹水型肝癌22A在发育末期的生长特性。放射自显影法显示,部分细胞可能处于G1期或R1期长达2天甚至4天;G2期的平均持续时间为16小时。55% - 60%的细胞处于延长的G1期和R1期,7%处于S期,9%处于G2期。其余25% - 30%的细胞显然不可逆地脱离有丝分裂周期,因为在分裂刺激后它们不参与增殖。