Burstyn P, Hornall D, Watchorn C
Br Med J. 1980 Aug 23;281(6239):537-9. doi: 10.1136/bmj.281.6239.537.
Sodium and potassium intakes were increased in normotensive volunteers to assess the effects on their blood pressures. An approximately threefold increase in sodium intake for eight days had no effect on the blood pressures of seven volunteers, while a two-stage increase in potassium intake, by about 40% for eight days and a further 55% for 14 days, had no effect on the blood pressures of 21 volunteers. Renal electrolyte excretions and the blood pressures of all 28 subjects showed no statistically significant correlations between either sodium or potassium excretion and blood pressure. A weak negative correlation was found between the sodium: potassium ratio and systolic pressure. The small reductions in sodium intake and increases in potassium intake that might be achieved through propaganda and changes in food processing are unlikely to lower mean blood pressure in Western societies.
在血压正常的志愿者中增加钠和钾的摄入量,以评估其对血压的影响。七名志愿者连续八天钠摄入量增加约三倍,但其血压未受影响;而21名志愿者的钾摄入量分两阶段增加,先是八天内增加约40%,随后14天再增加55%,其血压也未受影响。所有28名受试者的肾脏电解质排泄量与血压之间,无论是钠排泄量还是钾排泄量与血压之间均未显示出统计学上的显著相关性。钠钾比与收缩压之间存在微弱的负相关。通过宣传和改变食品加工方式可能实现的钠摄入量小幅减少和钾摄入量增加,不太可能降低西方社会的平均血压。