Lamming G D, Broughton Pipkin F, Symonds E M
Clin Exp Hypertens (1978). 1980;2(5):865-95. doi: 10.3109/10641968009037147.
Twentysix women with pregnancy-induced hypertension have been randomly treated with either labetalol or Aldomet. A more satisfactory control of blood pressure was obtained with labetalol with minimal side-effects. After two weeks of treatment with labetalol renal function had significantly improved with a markedly lower incidence of proteinuria. More patients went into spontaneous labour following labetalol than following Aldomet; the Bishop score was also higher in this group. No adverse effects attributable to labetalol were noted in the baby either ante- or post-natally.
26名妊娠高血压妇女被随机分为两组，分别接受拉贝洛尔或甲基多巴治疗。拉贝洛尔能更有效地控制血压，且副作用最小。使用拉贝洛尔治疗两周后，肾功能显著改善，蛋白尿发生率明显降低。与接受甲基多巴治疗的患者相比，接受拉贝洛尔治疗的患者更多地进入自然分娩；该组的Bishop评分也更高。在产前或产后，均未发现拉贝洛尔对婴儿有任何不良影响。
