Täger F
Fortschr Med. 1980 Jul 10;98(26-27):1036-8.
70 women aged 47-66 years, menopausal between 3 and 14 years and suffering from climacteric deficiency symptoms, were treated with estriol succinate. After 5 weeks of treatment the subjective symptoms had greatly subsided. 50 patients had an atrophic vaginal smear prior to treatment. In all cases this improved during therapy. In 8 out of 11 patients no change in the endometrial picture was observed. After the period of treatment a therapy free interval of 4 weeks followed, during which complaints increased in all cases. Besides the morphologic symptoms specially the symptoms flush and sweating were improved by therapy. Psychological complaints were influenced to a lesser degree.
70名年龄在47至66岁之间、绝经3至14年且患有更年期亏虚症状的女性接受了琥珀酸雌三醇治疗。治疗5周后，主观症状大为减轻。50名患者在治疗前阴道涂片显示萎缩性改变。在所有病例中，治疗期间这种情况均有改善。11名患者中有8名子宫内膜情况未见变化。治疗期结束后，接着有4周的无治疗间隔期，在此期间所有病例的症状均加重。除形态学症状外，潮热和出汗等症状经治疗后有所改善。心理方面的症状受影响程度较小。
