Förster H, Kasper M
Fortschr Med. 1980 Oct 9;98(38):1480-6.
Using 6 volunteers with obesity a carbohydrate accentuated balanced reduction diet (minimal diet) was investigated. The diet was composed per day of 50 g protein, 100 g carbohydrates, 11 g fat, distributed in five meals. Additionally, vitamins, electrolytes and trace elements are included in sufficient amounts. The ambulant volunteers were fully active during the dietary period which was without subjective side effects. During the dietary period a decrease in serum cholesterol and in triglycerides was found. The concentration of fatty acids and of kerone bodies was slightly elevated. Due to tubular acidosis, an increase in serum uric acid concentration was found, despite decreased renal loss of urate. Hyperinsulinemia due to obesity was normalized whereas glucose tolerance was not influenced to a greater extent during weight reduction diet. Whereas there are some quantitative metabolic alterations during carbohydrate accentuated minimal diet, these alterations are not alarming. The carbohydrate accentuated minimal diet is estimated to be optimum from the standpoint of a nutrionist. Reduction diets of alternative composition are judged to be inferior because of greater metabolic alterations.
对6名肥胖志愿者采用碳水化合物强化均衡低热量饮食（最低热量饮食）进行了研究。该饮食每天包含50克蛋白质、100克碳水化合物、11克脂肪，分五餐食用。此外，还含有足量的维生素、电解质和微量元素。这些门诊志愿者在饮食期间完全可以正常活动，且无主观副作用。在饮食期间，发现血清胆固醇和甘油三酯有所下降。脂肪酸和酮体的浓度略有升高。由于肾小管酸中毒，尽管尿酸肾排泄减少，但血清尿酸浓度仍有所升高。肥胖所致的高胰岛素血症恢复正常，而在减重饮食期间葡萄糖耐量未受到较大影响。虽然在碳水化合物强化最低热量饮食期间存在一些定量的代谢改变，但这些改变并不令人担忧。从营养学家的角度来看，碳水化合物强化最低热量饮食被认为是最佳的。由于存在更大的代谢改变，其他成分的低热量饮食被认为较差。
